Bibliographic Details
Title: |
TET3 prevents terminal differentiation of adult NSCs by a non-catalytic action at Snrpn |
Authors: |
Raquel Montalbán-Loro, Anna Lozano-Ureña, Mitsuteru Ito, Christel Krueger, Wolf Reik, Anne C. Ferguson-Smith, Sacri R. Ferrón |
Source: |
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019) |
Publisher Information: |
Nature Portfolio, 2019. |
Publication Year: |
2019 |
Collection: |
LCC:Science |
Subject Terms: |
Science |
More Details: |
The potential role of TET proteins in adult neurogenesis is unknown. In this study, authors show that TET3 is essentially required for the maintenance of the NSC pool in the adult subventricular zone niche by preventing premature differentiation of NSCs, via direct binding and repression of the paternal transcribed allele of the imprinted gene Snrpn |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-019-09665-1 |
Access URL: |
https://doaj.org/article/6a16a9a8341a4206bf85aaf5f9a6ae31 |
Accession Number: |
edsdoj.6a16a9a8341a4206bf85aaf5f9a6ae31 |
Database: |
Directory of Open Access Journals |