TET3 prevents terminal differentiation of adult NSCs by a non-catalytic action at Snrpn

Bibliographic Details
Title: TET3 prevents terminal differentiation of adult NSCs by a non-catalytic action at Snrpn
Authors: Raquel Montalbán-Loro, Anna Lozano-Ureña, Mitsuteru Ito, Christel Krueger, Wolf Reik, Anne C. Ferguson-Smith, Sacri R. Ferrón
Source: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Publisher Information: Nature Portfolio, 2019.
Publication Year: 2019
Collection: LCC:Science
Subject Terms: Science
More Details: The potential role of TET proteins in adult neurogenesis is unknown. In this study, authors show that TET3 is essentially required for the maintenance of the NSC pool in the adult subventricular zone niche by preventing premature differentiation of NSCs, via direct binding and repression of the paternal transcribed allele of the imprinted gene Snrpn
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-019-09665-1
Access URL: https://doaj.org/article/6a16a9a8341a4206bf85aaf5f9a6ae31
Accession Number: edsdoj.6a16a9a8341a4206bf85aaf5f9a6ae31
Database: Directory of Open Access Journals
More Details
ISSN:20411723
DOI:10.1038/s41467-019-09665-1
Published in:Nature Communications
Language:English