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Instrumental activities of daily living in older patients with metastatic prostate cancer: results from the meet-URO network ADHERE prospective study

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Title: Instrumental activities of daily living in older patients with metastatic prostate cancer: results from the meet-URO network ADHERE prospective study
Authors: Lucia Fratino, Jerry Polesel, Emilio Francesco Giunta, Marco Maruzzo, Sebastiano Buti, Mona Ali Hassan, Umberto Basso, Sara Elena Rebuzzi, Ugo De Giorgi, Marika Cinausero, Helga Lipari, Teresa Gamba, Davide Bimbatti, Arianna Dri, Paola Ermacora, Francesca Vignani, Giuseppe Fornarini, Pasquale Rescigno, Giuseppe Luigi Banna
Source: Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Publisher Information: Nature Portfolio, 2024.
Publication Year: 2024
Collection: LCC:Medicine
LCC:Science
Subject Terms: Medicine, Science
More Details: Abstract Instrumental activities of daily living (IADL) are significant health indicators closely related to executive functions and able to detect mild cognitive impairment. A decline in IADL usually precedes ADL limitation, including taking medications, and may therefore predict a cognitive decline. We aimed to investigate the association of patients’ IADL score with other clinical factors, with a particular focus on the presence of a caregiver, and the impact on adherence to androgen receptor pathway inhibitors (ARPIs) and survival outcomes within the Meet-URO 5—ADHERE study. It was a large prospective multicentre observational cohort study monitoring adherence to ARPIs in 234 metastatic castrate-resistant PC (mCRPC) patients aged ≥ 70. We observed an association between impaired IADL and lower geriatric G8 scores (p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2045-2322
Relation: https://doaj.org/toc/2045-2322
DOI: 10.1038/s41598-024-53581-4
Access URL: https://doaj.org/article/6a0ab27419da4917ac402a86c95934eb
Accession Number: edsdoj.6a0ab27419da4917ac402a86c95934eb
Database: Directory of Open Access Journals
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More Details
ISSN:20452322
DOI:10.1038/s41598-024-53581-4
Published in:Scientific Reports
Language:English