Bibliographic Details
| Title: |
Surgical complications of vagus nerve stimulation surgery: A 14-years single-center experience |
| Authors: |
Jouke van Schooten, Jacco Smeets, Sander MJ. van Kuijk, Sylvia Klinkenberg, Olaf E.M.G. Schijns, Jeske Nelissen, Louis G.L. Wagner, Rob P.W. Rouhl, Marian H.J.M. Majoie, Kim Rijkers |
| Source: |
Brain and Spine, Vol 4, Iss , Pp 102733- (2024) |
| Publisher Information: |
Elsevier, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Neurology. Diseases of the nervous system |
| Subject Terms: |
Vagus nerve stimulation, Epilepsy, Surgical complications, Neurology. Diseases of the nervous system, RC346-429 |
| More Details: |
Introduction: Vagus nerve stimulation (VNS) is the most frequently used neuromodulation treatment for Drug-Resistant Epilepsy (DRE) patients. Complications of VNS surgery include surgical site infection and unilateral vocal cord paresis. Complication rates vary across studies. Research question: What is the safety profile of VNS related surgeries? Materials and methods: Retrospective cohort study using patient files of DRE-patients who had undergone primary implantation of a VNS-system, replacement of the VNS pulse generator, replacement of the lead, replacement of both pulse generator and lead, or VNS removal surgery in the Maastricht UMC+. Multiple Imputation was used for missing data. Univariable and multivariable logistic regression analysis were performed to analyze possible risk factors, in case of a small sample size, an independent-samples t-test and Fisher's exact test or Pearson's X2-test were used. The complication rate was calculated as percentage. Results: This study included a total of 606 VNS surgical procedures, leading to 67 complications of which 3 permanent complications. Complication rate after primary implantation was 13.4%; 2,5% for pulse generator replacement; 21.4% for lead revision and 27.3% for complete VNS removal. No statistically significant results were found when analyzing the results of adults and children |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2772-5294 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S2772529423010214; https://doaj.org/toc/2772-5294 |
| DOI: |
10.1016/j.bas.2023.102733 |
| Access URL: |
https://doaj.org/article/a69e06c912154fe5a9b772461b134fff |
| Accession Number: |
edsdoj.69e06c912154fe5a9b772461b134fff |
| Database: |
Directory of Open Access Journals |
