Lean body mass predicts long-term survival in Chinese patients on peritoneal dialysis.

Bibliographic Details
Title: Lean body mass predicts long-term survival in Chinese patients on peritoneal dialysis.
Authors: Jenq-Wen Huang, Yu-Chung Lien, Hon-Yen Wu, Chung-Jen Yen, Chun-Chun Pan, Tsai-Wei Hung, Chi-Ting Su, Chih-Kang Chiang, Hui-Teng Cheng, Kuan-Yu Hung
Source: PLoS ONE, Vol 8, Iss 1, p e54976 (2013)
Publisher Information: Public Library of Science (PLoS), 2013.
Publication Year: 2013
Collection: LCC:Medicine
LCC:Science
Subject Terms: Medicine, Science
More Details: BACKGROUND: Reduced lean body mass (LBM) is one of the main indicators in malnutrition inflammation syndrome among patients on dialysis. However, the influence of LBM on peritoneal dialysis (PD) patients' outcomes and the factors related to increasing LBM are seldom reported. METHODS: We enrolled 103 incident PD patients between 2002 and 2003, and followed them until December 2011. Clinical characteristics, PD-associated parameters, residual renal function, and serum chemistry profiles of each patient were collected at 1 month and 1 year after initiating PD. LBM was estimated using creatinine index corrected with body weight. Multiple linear regression analysis, Kaplan-Meier survival analysis, and Cox regression proportional hazard analysis were used to define independent variables and compare survival between groups. RESULTS: Using the median LBM value (70% for men and 64% for women), patients were divided into group 1 (n = 52; low LBM) and group 2 (n = 51; high LBM). Group 1 patients had higher rates of peritonitis (1.6 vs. 1.1/100 patient months; p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1932-6203
Relation: http://europepmc.org/articles/PMC3555981?pdf=render; https://doaj.org/toc/1932-6203
DOI: 10.1371/journal.pone.0054976
Access URL: https://doaj.org/article/69cbb4d4b4fb4691bd2d85b0c1d69478
Accession Number: edsdoj.69cbb4d4b4fb4691bd2d85b0c1d69478
Database: Directory of Open Access Journals
More Details
ISSN:19326203
DOI:10.1371/journal.pone.0054976
Published in:PLoS ONE
Language:English