Analysis of 3-MCPD and 1,3-DCP occurrence in mayonnaise: A probabilistic risk assessment of dietary exposure for Iranians

Bibliographic Details
Title: Analysis of 3-MCPD and 1,3-DCP occurrence in mayonnaise: A probabilistic risk assessment of dietary exposure for Iranians
Authors: Seyedeh Faezeh Taghizadeh, Christina Tsitsimpikou, Aristidis Tsatsakis, Hadi Haghparast, Ghazaleh Tabriznia Tabrizi, Mahin Velayati, Gholamreza Karimi, Ramin Rezaee
Source: Toxicology Reports, Vol 13, Iss , Pp 101725- (2024)
Publisher Information: Elsevier, 2024.
Publication Year: 2024
Collection: LCC:Toxicology. Poisons
Subject Terms: Chloropropanols, Chronic oral exposure, High fat mayonnaise, Low fat mayonnaise, Regular daily intake, Toxicology. Poisons, RA1190-1270
More Details: Mayonnaise is a commonly used oil-in-water emulsion food product. Due to their toxicological properties/genotoxicity and carcinogenicity, chloropropanols’ oral exposure has raised concerns over the past decade. The present study reports the occurrence level of free forms of 3-chloropropane-1,2-diol (3-MCPD) and 1,3-dichloro-2-propanol (1,3-DCP) in mayonnaise samples and the risk of oral exposure to these chemicals through consumption of the analyzed samples. Mayonnaise (low- and high-fat, from 6 brands, totally 120 samples) were analyzed for 1,3-DCP and 3-MCPD by gas chromatography-mass spectrometry. The mean level of chemicals was higher in the high-fat samples, with no significant difference among the brands. Generally, 1,3-DCP level was significantly lower in both high-fat and low-fat samples compared to 3-MCPD. Hazard Index (HI) values calculated for oral exposure to 3-MCPD for Iranian adults using probabilistic methods, were less than 1.0, reflecting no major risk. In the Margin of Exposure scenario, low- and high-fat mayonnaise samples were of de minimis health concern at the 50th, 80th, and 95th centiles. Nevertheless, in order to safeguard consumer interests, it is imperative to implement online real-time methodologies for monitoring reactions that result in generation of thermal process contaminants such as 3-MCPD and 1,3-DCP, and to innovate novel technologies to minimize the occurrence of such chemicals while preserving both safety and sensory attributes.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2214-7500
Relation: http://www.sciencedirect.com/science/article/pii/S2214750024001082; https://doaj.org/toc/2214-7500
DOI: 10.1016/j.toxrep.2024.101725
Access URL: https://doaj.org/article/690feff7aa9247068bd7e18cf1579662
Accession Number: edsdoj.690feff7aa9247068bd7e18cf1579662
Database: Directory of Open Access Journals
More Details
ISSN:22147500
DOI:10.1016/j.toxrep.2024.101725
Published in:Toxicology Reports
Language:English