Bibliographic Details
| Title: |
Intravenous ferric carboxymaltose is associated with lowering of plasma phosphate levels in patients with gastric bypass surgery: a retrospective case series |
| Authors: |
Cindy Pereira Portela, Lucie Favre, Isabella Locatelli, Olivier Bonny |
| Source: |
Swiss Medical Weekly, Vol 154, Iss 7 (2024) |
| Publisher Information: |
SMW supporting association (Trägerverein Swiss Medical Weekly SMW), 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Medicine |
| Subject Terms: |
Medicine |
| More Details: |
AIMS: Bariatric surgery induces several micronutrient deficiencies that require supplementation. For iron, parenteral infusions are usually preferred over oral supplementation. Ferric carboxymaltose infusion has been associated with hypophosphataemia, mostly transient and asymptomatic. However, in some cases, ferric carboxymaltose-induced hypophosphataemia may persist for weeks to months and may induce muscle weakness, osteomalacia and bone fractures. The aim of this study was to identify possible predictors of a clinically relevant decrease in serum phosphate after ferric carboxymaltose infusion in patients with previous Roux-en-Y gastric bypass. METHODS: Patients with previous Roux-en-Y gastric bypass who received ferric carboxymaltose infusions between January 2018 and September 2019 and had recorded phosphataemia before and after ferric carboxymaltose infusion at the Lausanne University Hospital, Lausanne, Switzerland, were studied retrospectively. A multiple linear regression model was built with delta phosphataemia as the outcome to investigate the factors related to magnitude of serum phosphate lowering. RESULTS: Seventy-seven patients (70 females and 7 males) with previous Roux-en-Y gastric bypass were studied. Mean age (SD) was 43.2 (10.7) years and median BMI was 30.9 kg/m2 (IQR 27.9–36.4). Sixty-eight patients (88.3%) received an infusion of 500 mg ferric carboxymaltose and 9 patients (11.7%) received 250 mg ferric carboxymaltose. Forty-nine patients (63.6%) developed hypophosphataemia ( |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1424-3997 |
| Relation: |
https://smw.ch/index.php/smw/article/view/3771; https://doaj.org/toc/1424-3997 |
| DOI: |
10.57187/s.3771 |
| Access URL: |
https://doaj.org/article/68dca7bfe74d47da8e635bc5bdf69a3b |
| Accession Number: |
edsdoj.68dca7bfe74d47da8e635bc5bdf69a3b |
| Database: |
Directory of Open Access Journals |
