Academic Journal
The correlation between cumulative cigarette consumption and infarction-related coronary spasm in patients with ST-segment elevation acute myocardial infarction across different age groups
| Title: | The correlation between cumulative cigarette consumption and infarction-related coronary spasm in patients with ST-segment elevation acute myocardial infarction across different age groups |
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| Authors: | Zhihui Kuang, Lin Lin, Ranran Kong, Zhonghua Wang, Xianjun Mao, Dingcheng Xiang |
| Source: | Scientific Reports, Vol 15, Iss 1, Pp 1-9 (2025) |
| Publisher Information: | Nature Portfolio, 2025. |
| Publication Year: | 2025 |
| Collection: | LCC:Medicine LCC:Science |
| Subject Terms: | Cumulative cigarette consumption, Infarction-related coronary artery spasm, Acute ST-segment elevation myocardial infarction, Coronary angiography, Medicine, Science |
| More Details: | Abstract Coronary artery spasm (CAS) is a key contributor to the pathogenesis of acute ST-segment elevation myocardial infarction (STEMI). While smoking is recognized as a major risk factor for CAS, the relationship between cumulative cigarette consumption and infarction-related CAS across different age groups in STEMI patients remains unclear. This study aimed to investigate the correlation between cumulative cigarette consumption and infarction-related CAS across different age groups through a retrospective analysis. This retrospective study included STEMI patients who underwent coronary angiography (CAG) at the General Hospital of Southern Theater Command, between December 2014 and March 2018. STEMI was diagnosed based on the 2017 European Society of Cardiology (ESC) guidelines. Patients were divided into CAS and non-CAS groups according to CAG results, and further categorized by age into three groups: young (≤ 45 years), middle-aged (46–59 years), and elderly (≥ 60 years). Cumulative cigarette consumption was calculated using the smoking index (cigarettes/day × years). Smoking status was graded as follows: grade 0 (non-smokers), grade 1 (index ≤ 100), grade 2 (index > 100 and ≤ 200), and grade 3 (index > 200). Statistical analyses, including Chi-square tests, Spearman correlation, and multivariate logistic regression were conducted to evaluate the relationship between smoking and CAS in different age groups. Among the 1156 STEMI patients analyzed, 80 (6.9%) were diagnosed with CAS. The CAS group exhibited a higher proportion of young adults (35.0% vs. 13.8%, P |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2045-2322 |
| Relation: | https://doaj.org/toc/2045-2322 |
| DOI: | 10.1038/s41598-024-84125-5 |
| Access URL: | https://doaj.org/article/ac6805ecb17247e3bc26c8911e04f366 |
| Accession Number: | edsdoj.6805ecb17247e3bc26c8911e04f366 |
| Database: | Directory of Open Access Journals |
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| ISSN: | 20452322 |
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| DOI: | 10.1038/s41598-024-84125-5 |
| Published in: | Scientific Reports |
| Language: | English |