Academic Journal
Educational inequalities in aging‐related declines in fluid cognition and the onset of cognitive pathology
| Title: | Educational inequalities in aging‐related declines in fluid cognition and the onset of cognitive pathology |
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| Authors: | Sean A.P. Clouston, M. Maria Glymour, Graciela Muñiz Terrera |
| Source: | Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 1, Iss 3, Pp 303-310 (2015) |
| Publisher Information: | Wiley, 2015. |
| Publication Year: | 2015 |
| Collection: | LCC:Neurology. Diseases of the nervous system LCC:Geriatrics |
| Subject Terms: | Dementia, Aging, Neurology, Social medicine, Cognitive reserve, Educational status, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6 |
| More Details: | Abstract Background Education has been robustly associated with cognitive reserve and dementia, but not with the rate of cognitive aging, resulting in some confusion about the mechanisms of cognitive aging. This study uses longitudinal data to differentiate between trajectories indicative of healthy versus pathologic cognitive aging. Methods Participants included 9401 Health and Retirement Study respondents aged ≥55 years who completed cognitive testing regularly over 17.3 years until most recently in 2012. Individual‐specific random change‐point modeling was used to identify age of incident pathologic decline; acceleration is interpreted as indicating likely onset of pathologic decline when it is significant and negative. Results These methods detect incident dementia diagnoses with specificity/sensitivity of 89.3%/44.3%, 5.6 years before diagnosis. Each year of education was associated with 0.09 (95% confidence interval [CI], 0.087–0.096; P |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2352-8729 |
| Relation: | https://doaj.org/toc/2352-8729 |
| DOI: | 10.1016/j.dadm.2015.06.001 |
| Access URL: | https://doaj.org/article/67fc5fd00e04433b86eda2cd3cf43e6f |
| Accession Number: | edsdoj.67fc5fd00e04433b86eda2cd3cf43e6f |
| Database: | Directory of Open Access Journals |
| ISSN: | 23528729 |
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| DOI: | 10.1016/j.dadm.2015.06.001 |
| Published in: | Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring |
| Language: | English |