Multi-institutional retrospective analysis of ultrahypofractionated radiotherapy for Japanese prostate cancer patients

Bibliographic Details
Title:	Multi-institutional retrospective analysis of ultrahypofractionated radiotherapy for Japanese prostate cancer patients
Authors:	Hiromichi Ishiyama, Hideyasu Tsumura, Hisato Nagano, Motoi Watanabe, Eiichi Mizuno, Masashi Taka, Hiroaki Kobayashi, Takahisa Eriguchi, Hajime Imada, Koji Inaba, Katsumasa Nakamura
Source:	Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Publisher Information:	Nature Portfolio, 2021.
Publication Year:	2021
Collection:	LCC:Medicine LCC:Science
Subject Terms:	Medicine, Science
More Details:	Abstract To report outcomes and risk factors of ultrahypofractionated (UHF) radiotherapy for Japanese prostate cancer patients. This multi-institutional retrospective analysis comprised 259 patients with localized prostate cancer from 6 hospitals. A total dose of 35–36 Gy in 4–5 fractions was prescribed for sequential or alternate-day administration. Biochemical failure was defined according to the Phoenix ASTRO consensus. Toxicities were assessed using National Cancer Institute Common Toxicity Criteria version 4. Tumor control and toxicity rates were analyzed by competing risk frames. Median follow-up duration was 32 months (range 22–97 months). 2- and 3-year biochemical control rates were 97.7% and 96.4%, respectively. Initial prostate-specific antigen (p
Document Type:	article
File Description:	electronic resource
Language:	English
ISSN:	2045-2322
Relation:	https://doaj.org/toc/2045-2322
DOI:	10.1038/s41598-021-92307-8
Access URL:	https://doaj.org/article/677e0ef19ae74f80ac3d0cd39cbf41cc
Accession Number:	edsdoj.677e0ef19ae74f80ac3d0cd39cbf41cc
Database:	Directory of Open Access Journals
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More Details
ISSN:	20452322
DOI:	10.1038/s41598-021-92307-8
Published in:	Scientific Reports
Language:	English