Bibliographic Details
Title: |
SpotClean adjusts for spot swapping in spatial transcriptomics data |
Authors: |
Zijian Ni, Aman Prasad, Shuyang Chen, Richard B. Halberg, Lisa M. Arkin, Beth A. Drolet, Michael A. Newton, Christina Kendziorski |
Source: |
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022) |
Publisher Information: |
Nature Portfolio, 2022. |
Publication Year: |
2022 |
Collection: |
LCC:Science |
Subject Terms: |
Science |
More Details: |
Spatial transcriptomics experiments profile genome-wide gene expression at localized spots across a tissue. Here, the authors identify spot swapping, an artifact where RNA expressed at one tissue spot binds probes at another, and they propose SpotClean to adjust for it. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-022-30587-y |
Access URL: |
https://doaj.org/article/66cf14fee50f46db8fe773740c41da35 |
Accession Number: |
edsdoj.66cf14fee50f46db8fe773740c41da35 |
Database: |
Directory of Open Access Journals |