Dietary methionine sources and levels modulate the intestinal health status of broiler chickens

Bibliographic Details
Title: Dietary methionine sources and levels modulate the intestinal health status of broiler chickens
Authors: Lu Gong, Tahir Mahmood, Yves Mercier, Huiping Xu, Xiaodan Zhang, Yizhu Zhao, Yimeng Luo, Yuming Guo
Source: Animal Nutrition, Vol 15, Iss , Pp 242-255 (2023)
Publisher Information: KeAi Communications Co., Ltd., 2023.
Publication Year: 2023
Collection: LCC:Animal culture
Subject Terms: Chicken, Methionine, 2-Hydroxy-4-(methylthio)-butanoic acid, Intestinal health, Intestinal barrier, Animal culture, SF1-1100
More Details: Given the key role of methionine in biological processes, adequate methionine should be provided to meet the nutritional requirements. DL-2-hydroxy-4-(methylthio)-butanoic acid (DL-HMTBA) has been considered as an important source of methionine. However, the effects of different sources and levels of methionine on the intestinal health status have not been clarified yet. An experiment was carried out to investigate the effects of different dietary sources and levels of methionine on the intestinal epithelial barrier, inflammatory cytokines expression, ileal morphology, microbiota composition, and cecal short chain fatty acids (SCFA) profiles. For this purpose, 720 male Arbor Acre broiler chicks at 1 d old were randomly assigned to a 2 × 3 factorial arrangement with 2 methionine sources (DL-methionine and DL-HMTBA) and 3 total sulfur amino acids (TSAA) levels (80%, 100%, and 120% of Arbor Acre recommendation). The results showed that DL-HMTBA supplementation promoted intestinal physical barrier at both gene expression level of claudin-1 and serum diamine oxidase level (P
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2405-6545
Relation: http://www.sciencedirect.com/science/article/pii/S2405654523000938; https://doaj.org/toc/2405-6545
DOI: 10.1016/j.aninu.2023.07.004
Access URL: https://doaj.org/article/660d86bcf7c54210923cf93150d90299
Accession Number: edsdoj.660d86bcf7c54210923cf93150d90299
Database: Directory of Open Access Journals
More Details
ISSN:24056545
DOI:10.1016/j.aninu.2023.07.004
Published in:Animal Nutrition
Language:English