Value of SLE-DAS in assessing disease activity in patients with systemic lupus erythematosus: a single-centre retrospective study

Bibliographic Details
Title: Value of SLE-DAS in assessing disease activity in patients with systemic lupus erythematosus: a single-centre retrospective study
Authors: Leixi Xue, Zhichun Liu, Lin Zhang, Jinlu Ma, Mengxue Yan
Source: Lupus Science and Medicine, Vol 11, Iss 1 (2024)
Publisher Information: BMJ Publishing Group, 2024.
Publication Year: 2024
Collection: LCC:Immunologic diseases. Allergy
Subject Terms: Immunologic diseases. Allergy, RC581-607
More Details: Objectives This study aimed to evaluate the clinical value of the Systemic Lupus Erythematosus Disease Activity Score (SLE-DAS) for assessing disease activity in patients with SLE.Methods Clinical data were collected from patients with SLE who were admitted at the Second Affiliated Hospital of Soochow University from January 2009 to December 2022. The glucocorticoid dose grading was used as the gold standard for disease activity assessment in SLE. The SLE-DAS value was calculated, and the SLE disease activity status was graded based on the SLE-DAS value. Another scoring criterion, the SLE Disease Activity Index 2000 (SLEDAI 2000), served as a control. Spearman correlation analysis was used to calculate the correlation between the scoring criteria and other variables.Results The analysis included 396 patients with SLE. A strong correlation was found between SLE-DAS and SLEDAI 2000 (ρ=0.709, 95% CI 0.648 to 0.766, p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2053-8790
Relation: https://lupus.bmj.com/content/11/1/e001196.full; https://doaj.org/toc/2053-8790
DOI: 10.1136/lupus-2024-001196
Access URL: https://doaj.org/article/d65863f593af4159b94858891a76e368
Accession Number: edsdoj.65863f593af4159b94858891a76e368
Database: Directory of Open Access Journals
More Details
ISSN:20538790
DOI:10.1136/lupus-2024-001196
Published in:Lupus Science and Medicine
Language:English