Viral genotype and HLA class II alleles influence on extra-hepatic manifestations of chronic HCV infection

Bibliographic Details
Title:	Viral genotype and HLA class II alleles influence on extra-hepatic manifestations of chronic HCV infection
Authors:	M. Galeazzi, F. Bellisai, S. D'Alfonso, G. Morozzi, C. Giannitti
Source:	Reumatismo, Vol 60, Iss 3, Pp 192-198 (2011)
Publisher Information:	PAGEPress Publications, 2011.
Publication Year:	2011
Collection:	LCC:Medicine LCC:Internal medicine
Subject Terms:	Medicine, Internal medicine, RC31-1245
More Details:	Objective: To test whether an association between HCV genotype, HLA class II alleles distribution and extra-hepatic manifestations (EHM ) can be demonstrated in a group of Italian patients with chronic HCV infection . Methods: Sixty patients affected by HCV infection with EHM were consecutively enrolled. 163 HCV patients without EHM were tested as controls for the prevalence of HCV genotypes, while we referred to literature as to the controls for HLA distribution. HCV-RNA was quantified by a RT-PCR. HLA class II alleles typing was performed using a standard microlymphocytotoxicity assay. We used chi-square or Fisher test (p
Document Type:	article
File Description:	electronic resource
Language:	English Italian
ISSN:	0048-7449 2240-2683
Relation:	http://www.reumatismo.org/index.php/reuma/article/view/386; https://doaj.org/toc/0048-7449; https://doaj.org/toc/2240-2683
DOI:	10.4081/reumatismo.2008.192
Access URL:	https://doaj.org/article/656c9d3e722a4ca8bd99610dced494f8
Accession Number:	edsdoj.656c9d3e722a4ca8bd99610dced494f8
Database:	Directory of Open Access Journals