Efficacy of Topical 0.05% Isotretinoin Gel Versus 0.1% Adapalene Gel in The Treatment of Mild to Moderate Acne Vulgaris
| Title: | Efficacy of Topical 0.05% Isotretinoin Gel Versus 0.1% Adapalene Gel in The Treatment of Mild to Moderate Acne Vulgaris |
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| Authors: | Summaya Saleem, Naeem Raza, Nida Saleem, Saleem Ullah, Ghazala Yasmin, Farrah Yousaf |
| Source: | Pakistan Armed Forces Medical Journal, Vol 73, Iss 1 (2023) |
| Publisher Information: | Army Medical College Rawalpindi, 2023. |
| Publication Year: | 2023 |
| Collection: | LCC:Medicine LCC:Medicine (General) |
| Subject Terms: | Acne vulgaris, Adapalene gel, Isotretinoin gel, Efficacy, Medicine, Medicine (General), R5-920 |
| More Details: | Objective: To compare the efficacy of topical 0.05% Isotretinoin gel versus 0.1% Adapalene gel in treating mild to moderate acne vulgaris. Study Design: Quasi-Experimental study. Place and Duration of Study: Department of Dermatology, Pak Emirates Military Hospital (PEMH), Rawalpindi Pakistan, From Feb to Jul 2018. Methodology: A total of ninety-two patients aged 12 to 25 years with mild to moderate facial acne vulgaris were enrolled and divided into two treatment Groups, Group-A (0.05% Isotretinoin Gel) and Group-B (0.1% Adapalene Gel). Efficacy was measured at 12 weeks post-treatment. Results: Treatment was found efficacious in 84.8% (n=39/46) of patients in Group-A and 50.0% (n=23/46) of patients in Group-B (p= 0.001). There were similar results when treatment efficacy in both Groups was disease severity. In all cases,efficacy was better in Group-A (p |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 0030-9648 2411-8842 |
| Relation: | https://www.pafmj.org/index.php/PAFMJ/article/view/6472; https://doaj.org/toc/0030-9648; https://doaj.org/toc/2411-8842 |
| DOI: | 10.51253/pafmj.v73i1.6472 |
| Access URL: | https://doaj.org/article/e64d3a039edd404ab495caa5ebc70484 |
| Accession Number: | edsdoj.64d3a039edd404ab495caa5ebc70484 |
| Database: | Directory of Open Access Journals |
| ISSN: | 00309648 24118842 |
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| DOI: | 10.51253/pafmj.v73i1.6472 |
| Published in: | Pakistan Armed Forces Medical Journal |
| Language: | English |