Bibliographic Details
| Title: |
Metastatic follicular thyroid cancer with a longstanding responsiveness to gemcitabine plus oxaliplatin |
| Authors: |
Daniela Dias, Inês Damásio, Pedro Marques, Helder Simões, Ricardo Rodrigues, Branca Maria Cavaco, Valeriano Leite |
| Source: |
European Thyroid Journal, Vol 12, Iss 3, Pp 1-6 (2023) |
| Publisher Information: |
Bioscientifica, 2023. |
| Publication Year: |
2023 |
| Collection: |
LCC:Diseases of the endocrine glands. Clinical endocrinology |
| Subject Terms: |
advanced follicular thyroid carcinoma, gemox (gemcitabine plus oxaliplatin), multikinase inhibitors, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
| More Details: |
Background: Treatment of advanced follicular thyroid carcinoma (FTC) is based primarily on indirect evidence obtained with multikinase inhibitors (MKI) in clinical trials in which papillary carcinomas represent the vast majority of cases. However, it should be noted that MKI have a non-negligible toxicity that may decrease the patient’s quality of life. Conventional chemotherapy with GEMOX (gemcitabine plus oxaliplatin) is an off-label therapy, which seems to have some effectiveness in advanced diffe rentiated thyroid carcinomas, with a good safety profile, although further studies are needed. Case report: We report a case of a metastatic FTC, resistant to several lines of therapy. However, with a durable response to GEMOX, the overall survival of our patient appears to have been extended significantly due to this chemotherapy. Conclusion: GEMOX may have a role in patients with thyroid cancer unresponsive to MKI. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2235-0802 |
| Relation: |
https://etj.bioscientifica.com/view/journals/etj/12/3/ETJ-22-0227.xml; https://doaj.org/toc/2235-0802 |
| DOI: |
10.1530/ETJ-22-0227 |
| Access URL: |
https://doaj.org/article/64bd2f9e0d8c41a89065d357fab83384 |
| Accession Number: |
edsdoj.64bd2f9e0d8c41a89065d357fab83384 |
| Database: |
Directory of Open Access Journals |
