Bibliographic Details
| Title: |
Two roads for oncolytic immunotherapy development |
| Authors: |
Howard L. Kaufman, Praveen K. Bommareddy |
| Source: |
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-5 (2019) |
| Publisher Information: |
BMJ Publishing Group, 2019. |
| Publication Year: |
2019 |
| Collection: |
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: |
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: |
Abstract Oncolytic viruses are an emerging class of immunotherapy agents for cancer treatment. In this issue of JITC, Machiels et al. reports early phase data from an oncolytic adenovirus given by intravenous (IV) administration. While this may allow easy access to metastatic lesions, there is limited data supporting the therapeutic effectiveness of this approach. Further studies should include assessment of viral replication in tumor tissue and consider comparative trials using IV and intratumoral delivery to fully optimize oncolytic immunotherapy. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2051-1426 |
| Relation: |
http://link.springer.com/article/10.1186/s40425-019-0515-2; https://doaj.org/toc/2051-1426 |
| DOI: |
10.1186/s40425-019-0515-2 |
| Access URL: |
https://doaj.org/article/639dae61c57c458287a00f4d26a00b8f |
| Accession Number: |
edsdoj.639dae61c57c458287a00f4d26a00b8f |
| Database: |
Directory of Open Access Journals |
