Bibliographic Details
| Title: |
Antibiotic-resistant profile and the factors affecting the intravenous antibiotic treatment course of generalized Staphylococcal Scalded Skin Syndrome: a retrospective study |
| Authors: |
Tao Yang, Jiangyi Wang, Junya Cao, Xinyue Zhang, Yun Lai, Longnian Li, Xiaoying Ye, Cong You |
| Source: |
Italian Journal of Pediatrics, Vol 47, Iss 1, Pp 1-9 (2021) |
| Publisher Information: |
BMC, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Pediatrics |
| Subject Terms: |
Antibiotic sensitivity, Intravenous antibiotic treatment, Staphylococcal Scalded Skin Syndrome, S. aureus, Pediatrics, RJ1-570 |
| More Details: |
Abstract Background Staphylococcal Scalded Skin Syndrome (SSSS) is caused by a special type of Staphylococcus aureus (S.aureus) which can produce exfoliative toxins. The generalized SSSS is recommended to be admitted and treated with intravenous antibiotics. However, there were limited reports on whether personal and clinical factors can have impacts on the duration of intravenous antibiotic application for pediatric patients with generalized SSSS. We performed a study to assess the factors affecting intravenous antibiotic treatment course of SSSS patients. Additionally, the positive culture rates of S.aureus in different samples and the antibiotic-resistant profile were investigated. Methods Two hundred nineteen patients with generalized SSSS were included. Gender, age, area, season, maximum axillary temperature, white blood cell (WBC) count, C-reactive protein (CRP) level, types of intravenous antibiotics, and types of external antibiotics were recorded as the baseline. Simple linear regression was applied in the univariate analysis to determine the variables with statistical significance and then these variables were further examined in multivariate linear regression model. The positive culture rates of S.aureus in different sample sources were calculated and the drug sensitivity results were statistically compared by pairwise Chi square test. Results According to the multiple linear regression, older ages (β = − 0.01, p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1824-7288 |
| Relation: |
https://doaj.org/toc/1824-7288 |
| DOI: |
10.1186/s13052-021-01120-6 |
| Access URL: |
https://doaj.org/article/d6371405521e4ed38f8777b5e066234c |
| Accession Number: |
edsdoj.6371405521e4ed38f8777b5e066234c |
| Database: |
Directory of Open Access Journals |
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