Dosimetry for boron neutron capture therapy developed and verified at the accelerator based neutron source VITA

Bibliographic Details
Title: Dosimetry for boron neutron capture therapy developed and verified at the accelerator based neutron source VITA
Authors: Marina Bikchurina, Timofey Bykov, Ibrahim Ibrahim, Anna Kasatova, Dmitrii Kasatov, Iaroslav Kolesnikov, Victoria Konovalova, Timur Kormushakov, Alexey Koshkarev, Anton Kuznetsov, Vyacheslav Porosev, Sergey Savinov, Ivan Shchudlo, Nataliia Singatulina, Evgeniia Sokolova, Tatiana Sycheva, Iuliia Taskaeva, Gleb Verkhovod, Sergey Taskaev
Source: Frontiers in Nuclear Engineering, Vol 2 (2023)
Publisher Information: Frontiers Media S.A., 2023.
Publication Year: 2023
Collection: LCC:Nuclear and particle physics. Atomic energy. Radioactivity
Subject Terms: boron neutron capture therapy, charge particle accelerator, lithium target, dose, neutron detector, Plasma physics. Ionized gases, QC717.6-718.8, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
More Details: The method of boron neutron capture therapy for malignant tumors, proposed in 1936, is beginning to enter clinical practice. The development of dosimetry tools for characterization of therapeutic mixed neutron-photon beam and assessing the patient’s response to treatment is becoming relevant. In this work, a number of dosimetric techniques have been developed: a compact neutron detector with a pair of cast scintillators, one of which is enriched with boron, to measure the boron dose and the γ-ray dose; cell dosimeter for measuring the sum of the equivalent dose of fast neutrons and the equivalent nitrogen dose; prompt γ-ray spectroscopy for in situ measurement of boron dose in real time; epithermal neutron flux monitor for measuring the epithermal neutron flux. Their verification carried out on the accelerator based neutron source VITA showed that they can become convenient and reliable tools for characterization of neutron beam and assessing the patient’s response to treatment.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2813-3412
Relation: https://www.frontiersin.org/articles/10.3389/fnuen.2023.1266562/full; https://doaj.org/toc/2813-3412
DOI: 10.3389/fnuen.2023.1266562
Access URL: https://doaj.org/article/6358dff57fc84e8ab1cf2abc7b0f2c64
Accession Number: edsdoj.6358dff57fc84e8ab1cf2abc7b0f2c64
Database: Directory of Open Access Journals
More Details
ISSN:28133412
DOI:10.3389/fnuen.2023.1266562
Published in:Frontiers in Nuclear Engineering
Language:English