A case of pulmonary tumor thrombotic microangiopathy following lymphedema on the lower extremities

Bibliographic Details
Title: A case of pulmonary tumor thrombotic microangiopathy following lymphedema on the lower extremities
Authors: Yuri Shiraiwa, Yuri Taniguchi, Mari Hyoudou, Aya Shiba, Masaharu Aga, Kazuhito Miyazaki, Yusuke Hamakawa, Yuki Misumi, Yoko Agemi, Tsuneo Shimokawa, Chie Hasegawa, Hiroyuki Hayashi, Hiroaki Okamoto
Source: Respiratory Medicine Case Reports, Vol 37, Iss , Pp 101631- (2022)
Publisher Information: Elsevier, 2022.
Publication Year: 2022
Collection: LCC:Diseases of the respiratory system
Subject Terms: Pulmonary tumor thrombus microangiopathy, PTTM, Lymphedema, Adenocarcinoma, Unknown origin, Diseases of the respiratory system, RC705-779
More Details: Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare manifestation of malignancy. The antemortem diagnosis is difficult, since patients present with rapidly progressive symptoms. We recently observed a case of PTTM following lymphedema of the lower extremities. We did not reach a diagnosis, even after performing BAL and TBLB. The patient manifested pulmonary hypertension and died on the 9th day of admission. Autopsy revealed a tumor embolism in the pulmonary arterioles accompanied by fibrocellular epithelial cell proliferation, but the primary organ was not identified. To our knowledge, this is the first reported case of PTTM with lymphedema.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2213-0071
Relation: http://www.sciencedirect.com/science/article/pii/S2213007122000533; https://doaj.org/toc/2213-0071
DOI: 10.1016/j.rmcr.2022.101631
Access URL: https://doaj.org/article/62baeba8325d4f8e8384462320fb3543
Accession Number: edsdoj.62baeba8325d4f8e8384462320fb3543
Database: Directory of Open Access Journals
More Details
ISSN:22130071
DOI:10.1016/j.rmcr.2022.101631
Published in:Respiratory Medicine Case Reports
Language:English