Efficacy of Novel Ultrathin Single-Balloon Enteroscopy for Crohn’s Disease: A Propensity Score-Matched Study

Bibliographic Details
Title: Efficacy of Novel Ultrathin Single-Balloon Enteroscopy for Crohn’s Disease: A Propensity Score-Matched Study
Authors: Kaoru Takabayashi, Naoki Hosoe, Motohiko Kato, Yukie Hayashi, Ryoichi Miyanaga, Kosaku Nanki, Kayoko Fukuhara, Yohei Mikami, Shinta Mizuno, Tomohisa Sujino, Makoto Mutaguchi, Makoto Naganuma, Naohisa Yahagi, Haruhiko Ogata, Takanori Kanai
Source: Gut and Liver, Vol 14, Iss 5, Pp 619-625 (2020)
Publisher Information: Gastroenterology Council for Gut and Liver, 2020.
Publication Year: 2020
Collection: LCC:Diseases of the digestive system. Gastroenterology
Subject Terms: enteroscopy, single-balloon enteroscopy, ultrathin scope, crohn disease, Diseases of the digestive system. Gastroenterology, RC799-869
More Details: Background/Aims: The evaluation of small bowel lesions of Crohn’s disease (CD) using balloon-assisted enteroscopy (BAE) is crucial because mucosal healing is associated with a good prognosis. However, BAE procedures are invasive, requiring sedation or analgesia to reduce the patient’s pain. This study evaluated the clinical usefulness of a novel ultrathin single-balloon enteroscopy (SBE) procedure for CD. Methods: This single-center retrospective study included 102 CD patients who underwent trans-anal SBE between January 2012 and May 2018. Of these patients, 82 underwent enteroscopy using conventional SBE, while 20 underwent ultrathin SBE. Patients were analyzed using propensity score matching, with 20 patients per group. The median duration of the examination, terminal ileum intubation rate, median cecum intubation time, median insertion depth, adverse events, and sedated dose in each group were compared. Results: Before propensity score matching, the conventional SBE group had a larger number of surgical history patients than the ultrathin SBE group (p=0.05). After matching, the two groups did not significantly differ clinically. There were no significant differences in the mean duration of the examination, cecum intubation time, or terminal ileal intubation rate between ultrathin SBE and conventional SBE. The mean insertion depth of ultrathin SBE tended to be deeper than that of conventional SBE (p=0.09). The use of ultrathin SBE also reduced the sedative dose during needed for enteroscopy compared with conventional SBE (p=0.005). Conclusions: Novel ultrathin SBE may be less painful for CD patients than conventional SBE.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1976-2283
Relation: http://gutnliver.org/journal/view.html?doi=10.5009/gnl19228; https://doaj.org/toc/1976-2283
DOI: 10.5009/gnl19228
Access URL: https://doaj.org/article/62aee329a0df4858b4d5903cb4d1c3ea
Accession Number: edsdoj.62aee329a0df4858b4d5903cb4d1c3ea
Database: Directory of Open Access Journals
More Details
ISSN:19762283
DOI:10.5009/gnl19228
Published in:Gut and Liver
Language:English