Bibliographic Details
Title: |
Antagonizing cholecystokinin A receptor in the lung attenuates obesity-induced airway hyperresponsiveness |
Authors: |
Ronald Allan M. Panganiban, Zhiping Yang, Maoyun Sun, Chan Young Park, David I. Kasahara, Niccole Schaible, Ramaswamy Krishnan, Alvin T. Kho, Elliot Israel, Marc B. Hershenson, Scott T. Weiss, Blanca E. Himes, Jeffrey J. Fredberg, Kelan G. Tantisira, Stephanie A. Shore, Quan Lu |
Source: |
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023) |
Publisher Information: |
Nature Portfolio, 2023. |
Publication Year: |
2023 |
Collection: |
LCC:Science |
Subject Terms: |
Science |
More Details: |
The underlying mechanisms of how obesity increases asthma prevalence and severity are not well understood. Here, the authors show that antagonizing cholecystokinin and its receptor, CCKAR, in the lung attenuates obesity-associated airway hyperresponsiveness in mice. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-022-35739-8 |
Access URL: |
https://doaj.org/article/627590137e8e4854b2f7c749238e36dd |
Accession Number: |
edsdoj.627590137e8e4854b2f7c749238e36dd |
Database: |
Directory of Open Access Journals |