Antagonizing cholecystokinin A receptor in the lung attenuates obesity-induced airway hyperresponsiveness

Bibliographic Details
Title: Antagonizing cholecystokinin A receptor in the lung attenuates obesity-induced airway hyperresponsiveness
Authors: Ronald Allan M. Panganiban, Zhiping Yang, Maoyun Sun, Chan Young Park, David I. Kasahara, Niccole Schaible, Ramaswamy Krishnan, Alvin T. Kho, Elliot Israel, Marc B. Hershenson, Scott T. Weiss, Blanca E. Himes, Jeffrey J. Fredberg, Kelan G. Tantisira, Stephanie A. Shore, Quan Lu
Source: Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Publisher Information: Nature Portfolio, 2023.
Publication Year: 2023
Collection: LCC:Science
Subject Terms: Science
More Details: The underlying mechanisms of how obesity increases asthma prevalence and severity are not well understood. Here, the authors show that antagonizing cholecystokinin and its receptor, CCKAR, in the lung attenuates obesity-associated airway hyperresponsiveness in mice.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-022-35739-8
Access URL: https://doaj.org/article/627590137e8e4854b2f7c749238e36dd
Accession Number: edsdoj.627590137e8e4854b2f7c749238e36dd
Database: Directory of Open Access Journals
More Details
ISSN:20411723
DOI:10.1038/s41467-022-35739-8
Published in:Nature Communications
Language:English