Acute Hepatitis Induced by Intravesical BCG Therapy: A Rare but Serious Complication

Bibliographic Details
Title:	Acute Hepatitis Induced by Intravesical BCG Therapy: A Rare but Serious Complication
Authors:	Hakima Abid, Mouna Figuigui, Sidi Adil Ibrahimi, Mohamed El Abkari, Mohamed Mzyiene, Soufiane Ennaciri, Ouima Justin Ziba, Mohamed Jamal El Fassi, Layla Tahiri Elousrouti, Laila Chbani
Source:	Case Reports in Hepatology, Vol 2021 (2021)
Publisher Information:	Wiley, 2021.
Publication Year:	2021
Collection:	LCC:Diseases of the digestive system. Gastroenterology
Subject Terms:	Diseases of the digestive system. Gastroenterology, RC799-869
More Details:	Bacillus Calmette and Guérin (BCG), widely used as a vaccination to prevent tuberculosis, is also used as immunotherapy, by intrabladder instillation, to treat superficial bladder cancers and prevent recurrence. Complications following instillation of BCG are most often localized reactions, such as cystitis or hematuria. They can more rarely be generalized and potentially severe such as hepatitis, pneumopathies, aortitis, and localization to hematopoietic tissue. We have reported the observation of a 47-year-old patient followed up for a bladder tumor operated for transurethral resection of the bladder, then having benefited from an instillation of BCG therapy complicated by occurrence a week later of an acute hepatitis. The diagnostic time was 2 days, and the outcome was favorable with corticosteroid therapy.
Document Type:	article
File Description:	electronic resource
Language:	English
ISSN:	2090-6587 2090-6595
Relation:	https://doaj.org/toc/2090-6587; https://doaj.org/toc/2090-6595
DOI:	10.1155/2021/4574879
Access URL:	https://doaj.org/article/6142073b78c74d2d8da06e054e4b18e6
Accession Number:	edsdoj.6142073b78c74d2d8da06e054e4b18e6
Database:	Directory of Open Access Journals

More Details
ISSN:	20906587 20906595
DOI:	10.1155/2021/4574879
Published in:	Case Reports in Hepatology
Language:	English