Bibliographic Details
| Title: |
Regnase-1-mediated post-transcriptional regulation is essential for hematopoietic stem and progenitor cell homeostasis |
| Authors: |
Hiroyasu Kidoya, Fumitaka Muramatsu, Teppei Shimamura, Weizhen Jia, Takashi Satoh, Yumiko Hayashi, Hisamichi Naito, Yuya Kunisaki, Fumio Arai, Masahide Seki, Yutaka Suzuki, Tsuyoshi Osawa, Shizuo Akira, Nobuyuki Takakura |
| Source: |
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019) |
| Publisher Information: |
Nature Portfolio, 2019. |
| Publication Year: |
2019 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
Regnase-1 is known to mediate post-trasncriptional regulatory activity through degradation of target mRNAs. Here, the authors show that Regnase-1 regulates self-renewal of haematopoietic stem and progenitor cells through modulation of the stability of Gata2 and Tal1 mRNA. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-019-09028-w |
| Access URL: |
https://doaj.org/article/60ea1588085a4c4e8b2d1deefdae9a0c |
| Accession Number: |
edsdoj.60ea1588085a4c4e8b2d1deefdae9a0c |
| Database: |
Directory of Open Access Journals |
