Bibliographic Details
| Title: |
Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease |
| Authors: |
Anissa A. Widjaja, Sivakumar Viswanathan, Shamini G. Shekeran, Eleonora Adami, Wei-Wen Lim, Sonia Chothani, Jessie Tan, Joyce Wei Ting Goh, Hui Mei Chen, Sze Yun Lim, Carine M. Boustany-Kari, Julie Hawkins, Enrico Petretto, Norbert Hübner, Sebastian Schafer, Thomas M. Coffman, Stuart A. Cook |
| Source: |
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022) |
| Publisher Information: |
Nature Portfolio, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
Repair processes in kidney are impaired in severe disease. Here, the authors show that in kidney failure, genetic or pharmacologic inhibition of IL11 releases the brake on regeneration, reverses tissue damage and restores kidney function. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-022-35306-1 |
| Access URL: |
https://doaj.org/article/60e0f4d907fc4280bc1f88c1b900af64 |
| Accession Number: |
edsdoj.60e0f4d907fc4280bc1f88c1b900af64 |
| Database: |
Directory of Open Access Journals |
