Acute disseminated encephalomyelitis associated with SARS-CoV-2 in a 21-month-old: a case report
| Title: | Acute disseminated encephalomyelitis associated with SARS-CoV-2 in a 21-month-old: a case report |
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| Authors: | Cecília Gomes-Pereira, Beatriz Sousa, Sara Nogueira-Machado, Valentina Ribeiro, Catarina Magalhães |
| Source: | Portuguese Journal of Pediatrics, Vol 55, Iss 2 (2024) |
| Publisher Information: | Publicaciones Permanyer, 2024. |
| Publication Year: | 2024 |
| Collection: | LCC:Pediatrics LCC:Medicine (General) |
| Subject Terms: | ADEM. SARS-CoV-2. Encephalitis., Pediatrics, RJ1-570, Medicine (General), R5-920 |
| More Details: | Introduction: Since its emergence in 2019, SARS-CoV-2 has been responsible for a myriad of symptoms affecting multiple organ systems, including the central nervous system. Although rare, especially in children, cases of acute disseminated encephalomyelitis (ADEM) associated with COVID-19 have also been described. Case report: We present the case of a previously healthy 21-month-old girl who presented with altered consciousness and ataxia ten days after SARS-CoV-2 infection was reported. Cranioencephalic MRI revealed hyperintense T2-weighted and hypointense T1-weighted lesions. The remaining imaging, analytical, autoimmune, and serological studies showed no alterations, allowing a diagnosis to be established. Therapy with pulses of prednisolone was initiated with excellent results. Discussion: This case report highlights the importance of a high index of suspicion in a child presenting with encephalopathy days to weeks after SARS-CoV-2 infection. A quick diagnosis is vital for early treatment and to improve the clinical course and long-term outcome. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English Portuguese |
| ISSN: | 2184-4453 |
| Relation: | https://pjp.spp.pt/frame_eng.php?id=70; https://doaj.org/toc/2184-4453 |
| DOI: | 10.24875/PJP.M24000446 |
| Access URL: | https://doaj.org/article/6092c62accf34d74b5533b20c2d05e03 |
| Accession Number: | edsdoj.6092c62accf34d74b5533b20c2d05e03 |
| Database: | Directory of Open Access Journals |
| ISSN: | 21844453 |
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| DOI: | 10.24875/PJP.M24000446 |
| Published in: | Portuguese Journal of Pediatrics |
| Language: | English Portuguese |