Main Components of Fish Immunity: An Overview of the Fish Immune System

Bibliographic Details
Title: Main Components of Fish Immunity: An Overview of the Fish Immune System
Authors: Doaa M. Mokhtar, Giacomo Zaccone, Alessio Alesci, Michal Kuciel, Manal T. Hussein, Ramy K. A. Sayed
Source: Fishes, Vol 8, Iss 2, p 93 (2023)
Publisher Information: MDPI AG, 2023.
Publication Year: 2023
Collection: LCC:Biology (General)
LCC:Genetics
Subject Terms: teleosts, mucosal immunity, cytokines, secretory immunoglobulins, antigen processing, immune cells, Biology (General), QH301-705.5, Genetics, QH426-470
More Details: Cellular immune responses consist of innate and adaptive cell-mediated immune mechanisms, where all leukocyte subpopulations are included. Among these are vital processes such as cell-mediated cytotoxicity and phagocytosis. The main cellular constituents of the fish immune system are macrophages, granulocytes, dendritic cells, NK cells, and cytotoxic T cells. This review provides the latest information on cellular defense mechanisms of fish and provides an overview of the function of the mucosal immune system in maintaining the general health of fish. Here, we discuss the fundamental ideas that underpin mucosal immune responses in teleosts, as well as the innate and adaptive immune cells and the molecules that play a role in these immune responses. Moreover, cytokine molecules and pathways in teleosts have been reported to focus on several kinds of associated immunity. Importantly, we also review antigen processing and presentation. The knowledge reported here will enable better understanding, determination, and modulation of the pathways responsible for protective immunity, thus consequently improving the health of the fish in aquaculture.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2410-3888
Relation: https://www.mdpi.com/2410-3888/8/2/93; https://doaj.org/toc/2410-3888
DOI: 10.3390/fishes8020093
Access URL: https://doaj.org/article/60613e81ab324f9aa9209118467d8eb8
Accession Number: edsdoj.60613e81ab324f9aa9209118467d8eb8
Database: Directory of Open Access Journals
More Details
ISSN:24103888
DOI:10.3390/fishes8020093
Published in:Fishes
Language:English