CCMetagen: comprehensive and accurate identification of eukaryotes and prokaryotes in metagenomic data

Bibliographic Details
Title: CCMetagen: comprehensive and accurate identification of eukaryotes and prokaryotes in metagenomic data
Authors: Vanessa R. Marcelino, Philip T. L. C. Clausen, Jan P. Buchmann, Michelle Wille, Jonathan R. Iredell, Wieland Meyer, Ole Lund, Tania C. Sorrell, Edward C. Holmes
Source: Genome Biology, Vol 21, Iss 1, Pp 1-15 (2020)
Publisher Information: BMC, 2020.
Publication Year: 2020
Collection: LCC:Biology (General)
LCC:Genetics
Subject Terms: Microbiome, Metagenomic classifier, ConClave sorting, Fungi, Biology (General), QH301-705.5, Genetics, QH426-470
More Details: Abstract There is an increasing demand for accurate and fast metagenome classifiers that can not only identify bacteria, but all members of a microbial community. We used a recently developed concept in read mapping to develop a highly accurate metagenomic classification pipeline named CCMetagen. The pipeline substantially outperforms other commonly used software in identifying bacteria and fungi and can efficiently use the entire NCBI nucleotide collection as a reference to detect species with incomplete genome data from all biological kingdoms. CCMetagen is user-friendly, and the results can be easily integrated into microbial community analysis software for streamlined and automated microbiome studies.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1474-760X
Relation: http://link.springer.com/article/10.1186/s13059-020-02014-2; https://doaj.org/toc/1474-760X
DOI: 10.1186/s13059-020-02014-2
Access URL: https://doaj.org/article/603ad5e8d3794c12b57c37afbe8c7179
Accession Number: edsdoj.603ad5e8d3794c12b57c37afbe8c7179
Database: Directory of Open Access Journals
More Details
ISSN:1474760X
DOI:10.1186/s13059-020-02014-2
Published in:Genome Biology
Language:English