Bibliographic Details
| Title: |
Outcomes and safety of mechanical thrombectomy, alteplase, and conventional medical care in the treatment of acute M2 segment middle cerebral artery occlusion: a comparative study |
| Authors: |
Eman M. Khedr, Ahmed Elbassiouny, Mahmoud Nageeb, Ahmed Aly, Khalid O. Mohamed, Nourelhoda A. Haridy |
| Source: |
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, Vol 61, Iss 1, Pp 1-12 (2025) |
| Publisher Information: |
SpringerOpen, 2025. |
| Publication Year: |
2025 |
| Collection: |
LCC:Neurosciences. Biological psychiatry. Neuropsychiatry |
| Subject Terms: |
Mechanical thrombectomy, rTPA, M2 segment, Catheter retrieval, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571 |
| More Details: |
Abstract Background Data on mechanical thrombectomy (MT) to treat M2 occlusions of the middle cerebral artery (MCA) are sparse. We report the outcome and safety of MT versus intravenous recombinant tissue plasminogen activator (IV rTPA) versus conventional medical treatment (CMT) of acute ischemic stroke (AIS) due to occlusion of the M2 segment of the MCA. This prospective longitudinal intervention study compared the outcomes and safety of MT, rTPA, and CMT in M2 occlusion AIS patients. National Institutes of Health Stroke Scale (NIHSS), modified Rankin scale (mRS), and recanalization rate assessed outcomes. Results 74 AIS patients were recruited (23 MT, 23 rTPA, 28CMT). MT group had significantly higher admission NIHSS (p = 0.018) and mRS (p = 0.023) than rTPA. At 24 h, NIHSS improved more with MT and rTPA than CMT (p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1687-8329 |
| Relation: |
https://doaj.org/toc/1687-8329 |
| DOI: |
10.1186/s41983-025-00935-y |
| Access URL: |
https://doaj.org/article/a6025f3c5e174fddb0527b48878b7282 |
| Accession Number: |
edsdoj.6025f3c5e174fddb0527b48878b7282 |
| Database: |
Directory of Open Access Journals |
|
Full text is not displayed to guests. |
Login for full access.
|
