Bibliographic Details
| Title: |
Acupuncture treatment is associated with a decreased risk of dementia in patients with rheumatoid arthritis in Taiwan: A propensity-score matched cohort study |
| Authors: |
Hou-Hsun Liao, Ming-Cheng Huang, Yu-Chen Lee, Cheng-Li Lin, Mei-Yao Wu, Peter Karl Mayer, Hung-Rong Yen |
| Source: |
Integrative Medicine Research, Vol 13, Iss 4, Pp 101086- (2024) |
| Publisher Information: |
Elsevier, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Miscellaneous systems and treatments |
| Subject Terms: |
Acupuncture, Dementia, Real-word data, Rheumatoid arthritis, Traditional Chinese medicine, Miscellaneous systems and treatments, RZ409.7-999 |
| More Details: |
Background: The purpose of this study was to understand whether acupuncture can decrease the risk of dementia in patients with rheumatoid arthritis (RA). Methods: Using the registry from the National Health Insurance Research Database of Taiwan, we carried out a 1:1 propensity-score matched cohort study to analyze patients with RA diagnosed between 2000 and 2010. The patients who received acupuncture therapy were grouped as acupuncture users (n = 9,919), while the others were grouped as non-acupuncture users (n = 19,331). After propensity-score matching, the final sample included 9,218 matched participants in both groups, and these participants were followed up until the end of 2011. We used a Cox regression model to adjust for age, sex, comorbidiy, and conventional drugs and compared the hazard ratios (HRs) of developing dementia in the acupuncture and non-acupuncture groups. Results: Acupuncture users tended to be more female-dominant and younger than non-acupuncture users. After propensity-score matching, both groups have comparable demographic characteristics. Acupuncture users had a lower risk of dementia than non-acupuncture users (adjusted HR: 0.55, 95% CI: 0.46–0.66). The cumulative incidence of dementia in the acupuncture group was significantly lower than that in the non-acupuncture group (log-rank test, p < 0.001). Patients who received the combinational treatment of conventional drugs and acupuncture had a significantly lower risk of developing dementia (adjusted HR: 0.64, 95% CI: 0.56–0.73) compared to those who only received conventional drugs. Conclusion: Acupuncture therapy is associated with a reduced risk of dementia in patients with RA. Further clinical and mechanistic studies are needed. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2213-4220 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S2213422024000660; https://doaj.org/toc/2213-4220 |
| DOI: |
10.1016/j.imr.2024.101086 |
| Access URL: |
https://doaj.org/article/5e91c55fdb5f4cfc86005900a1fdc74f |
| Accession Number: |
edsdoj.5e91c55fdb5f4cfc86005900a1fdc74f |
| Database: |
Directory of Open Access Journals |
