| Title: |
Reliable identification of protein-protein interactions by crosslinking mass spectrometry |
| Authors: |
Swantje Lenz, Ludwig R. Sinn, Francis J. O’Reilly, Lutz Fischer, Fritz Wegner, Juri Rappsilber |
| Source: |
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021) |
| Publisher Information: |
Nature Portfolio, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
Cross-linking mass spectrometry (MS) can identify protein-protein interaction (PPI) networks but assessing the reliability of these data remains challenging. To address this issue, the authors develop and validate a method to determine the false-discovery rate of PPIs identified by cross-linking MS. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-021-23666-z |
| Access URL: |
https://doaj.org/article/5e27def07ee34f139b97a8e8b802239b |
| Accession Number: |
edsdoj.5e27def07ee34f139b97a8e8b802239b |
| Database: |
Directory of Open Access Journals |
