EFFECTS OF RENAL ARTERY DENERVATION ON LEFT VENTRICULAR DEFORMATION AND BLOOD FLOW VELOCITY IN THE DISTAL SEGMENT OF ANTERIOR DESCENDING CORONARY ARTERY AMONG PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION
| Title: | EFFECTS OF RENAL ARTERY DENERVATION ON LEFT VENTRICULAR DEFORMATION AND BLOOD FLOW VELOCITY IN THE DISTAL SEGMENT OF ANTERIOR DESCENDING CORONARY ARTERY AMONG PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION |
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| Authors: | E. N. Pavlukova, V. F. Mordovin, V. V. Pekarskyi, V. A. Lichikaki, R. S. Karpov |
| Source: | Российский кардиологический журнал, Vol 0, Iss 4, Pp 100-107 (2014) |
| Publisher Information: | «FIRMA «SILICEA» LLC, 2014. |
| Publication Year: | 2014 |
| Collection: | LCC:Diseases of the circulatory (Cardiovascular) system |
| Subject Terms: | resistant arterial hypertension, renal artery denervation, left ventricular deformation, speckle tracking imaging (2d strain), coronary blood flow, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| More Details: | Aim. To assess the dynamics of left ventricular (LV) longitudinal deformation and blood flow velocity in the distal segment of anterior descending coronary artery (ADCA) among patients with resistant arterial hypertension (AH) 12 months after renal artery denervation.Material and methods. In seven patients with resistant AH (mean age 52,00±6,59 years), bilateral renal artery denervation was performed. Five out of seven patients had concentric LV hypertrophy. The complex clinical and instrumental examination included the assessment of office and 24-hour blood pressure (BP) levels, echocardiography, speckle tracking imaging (2D strain), and transthoracic visualisation of the distal segment of ADCA.Results. Twelve months after renal artery denervation, office BP levels decreased by 31/20 mm Hg. Mean 24-hour, mean daytime, and mean nighttime BP levels reduced by 15,58/14,62 mm Hg, 17,1/14,9 mm Hg, and by 21,1/14,47 mm Hg, respectively. There was an increase in global longitudinal LV deformation and local LV deformation (basal septal segment, basal and middle segments ofanterior and posterior walls, and middle and apical segments of lateral wall). The improvement in longitudinal systolic LV function was associated with reduced linear velocity of diastolic blood flow in the distal ADCA segment, without similar systolic changes.Conclusion. Our results suggest that renal artery denervation is linked to improved LV function; therefore, this method could be widely recommended for the management of patients with resistant AH. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | Russian |
| ISSN: | 1560-4071 2618-7620 |
| Relation: | https://russjcardiol.elpub.ru/jour/article/view/44; https://doaj.org/toc/1560-4071; https://doaj.org/toc/2618-7620 |
| DOI: | 10.15829/1560-4071-2014-4-100-107 |
| Access URL: | https://doaj.org/article/5ded014c3cdd4ade96ee074b7fdfb056 |
| Accession Number: | edsdoj.5ded014c3cdd4ade96ee074b7fdfb056 |
| Database: | Directory of Open Access Journals |
| ISSN: | 15604071 26187620 |
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| DOI: | 10.15829/1560-4071-2014-4-100-107 |
| Published in: | Российский кардиологический журнал |
| Language: | Russian |