Bibliographic Details
| Title: |
Associations of Uric Acid With Liver Steatosis and Fibrosis Applying Vibration Controlled Transient Elastography in the United States: A Nationwide Cross-Section Study |
| Authors: |
Hualin Duan, Rong Zhang, Xingying Chen, Genfeng Yu, Cheng Song, Yuqi Jiang, Yajun He, Heng Wan, Jie Shen |
| Source: |
Frontiers in Endocrinology, Vol 13 (2022) |
| Publisher Information: |
Frontiers Media S.A., 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Diseases of the endocrine glands. Clinical endocrinology |
| Subject Terms: |
liver steatosis, liver fibrosis, controlled attenuation parameter, liver stiffness measurement, uric acid, NHANES, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
| More Details: |
Background and objectiveSerum uric acid (UA) is related to many metabolic diseases. However, the association of UA with liver diseases was not very clear. The objective of this study is to clarify the relationship of UA with liver steatosis and fibrosis.MethodsThis is a cross-sectional study of 4364 people of National Health and Nutrition Examination Survey (NHANES) 2017-2018. Liver steatosis and fibrosis were assessed by controlled attenuation parameter (CAP) and liver stiffness measurements (LSM) using Vibration-controlled transient elastography (VCTE). Linear and logistic regressions were performed.ResultsAfter adjusting for potential confounders, UA levels were associated with the prevalence of liver steatosis [OR=2.097 (95%CI: 1.245, 3.534)] and liver fibrosis [OR=2.983 (95%CI: 1.797, 4.952)]. Furthermore, the results were consistent in the subgroup analyses of males and females.ConclusionsUA levels were positively associated with the prevalence of liver steatosis and fibrosis. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1664-2392 |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fendo.2022.930224/full; https://doaj.org/toc/1664-2392 |
| DOI: |
10.3389/fendo.2022.930224 |
| Access URL: |
https://doaj.org/article/cd5d7e9219c64071b1a90c0c33472781 |
| Accession Number: |
edsdoj.5d7e9219c64071b1a90c0c33472781 |
| Database: |
Directory of Open Access Journals |
