Bibliographic Details
Title: |
Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation |
Authors: |
Jingxue Xin, Hui Zhang, Yaoxi He, Zhana Duren, Caijuan Bai, Lang Chen, Xin Luo, Dong-Sheng Yan, Chaoyu Zhang, Xiang Zhu, Qiuyue Yuan, Zhanying Feng, Chaoying Cui, Xuebin Qi, Ouzhuluobu, Wing Hung Wong, Yong Wang, Bing Su |
Source: |
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020) |
Publisher Information: |
Nature Portfolio, 2020. |
Publication Year: |
2020 |
Collection: |
LCC:Science |
Subject Terms: |
Science |
More Details: |
Tibetan adaptation to the high-altitude environment represents a case of natural selection during recent human evolution. Here the authors investigated the chromatin and transcriptional landscape of umbilical endothelial cells from Tibetan and Han Chinese donors and provide genome-wide characterization of the hypoxia regulatory network associated high-altitude adaptation. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-020-18638-8 |
Access URL: |
https://doaj.org/article/5d727e2e509d4204b777b2789c0541c6 |
Accession Number: |
edsdoj.5d727e2e509d4204b777b2789c0541c6 |
Database: |
Directory of Open Access Journals |