Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation

Bibliographic Details
Title: Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation
Authors: Jingxue Xin, Hui Zhang, Yaoxi He, Zhana Duren, Caijuan Bai, Lang Chen, Xin Luo, Dong-Sheng Yan, Chaoyu Zhang, Xiang Zhu, Qiuyue Yuan, Zhanying Feng, Chaoying Cui, Xuebin Qi, Ouzhuluobu, Wing Hung Wong, Yong Wang, Bing Su
Source: Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Publisher Information: Nature Portfolio, 2020.
Publication Year: 2020
Collection: LCC:Science
Subject Terms: Science
More Details: Tibetan adaptation to the high-altitude environment represents a case of natural selection during recent human evolution. Here the authors investigated the chromatin and transcriptional landscape of umbilical endothelial cells from Tibetan and Han Chinese donors and provide genome-wide characterization of the hypoxia regulatory network associated high-altitude adaptation.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-020-18638-8
Access URL: https://doaj.org/article/5d727e2e509d4204b777b2789c0541c6
Accession Number: edsdoj.5d727e2e509d4204b777b2789c0541c6
Database: Directory of Open Access Journals
More Details
ISSN:20411723
DOI:10.1038/s41467-020-18638-8
Published in:Nature Communications
Language:English