Bibliographic Details
| Title: |
Validation of 18F-FDG PET/MRI and diffusion-weighted MRI for estimating the extent of peritoneal carcinomatosis in ovarian and endometrial cancer -a pilot study |
| Authors: |
Björg Jónsdóttir, Montserrat Alemany Ripoll, Antonina Bergman, Ilvars Silins, Inger Sundström Poromaa, Håkan Ahlström, Karin Stålberg |
| Source: |
Cancer Imaging, Vol 21, Iss 1, Pp 1-10 (2021) |
| Publisher Information: |
BMC, 2021. |
| Publication Year: |
2021 |
| Collection: |
LCC:Medical physics. Medical radiology. Nuclear medicine
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: |
PET/MRI, DW-MRI, Ovarian cancer, Peritoneal cancer index (PCI), Carcinomatosis, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: |
Abstract Background The extent of peritoneal carcinomatosis is difficult to estimate preoperatively, but a valid measure would be important in identifying operable patients. The present study set out to validate the usefulness of integrated 18F-FDG PET/MRI, in comparison with diffusion-weighted MRI (DW-MRI), for estimation of the extent of peritoneal carcinomatosis in patients with gynaecological cancer. Methods Whole-body PET/MRI was performed on 34 patients with presumed carcinomatosis of gynaecological origin, all scheduled for surgery. Two radiologists evaluated the peritoneal cancer index (PCI) on PET/MRI and DW-MRI scans in consensus. The surgeon estimated PCI intraoperatively, which was used as the gold standard. Results Median total PCI for PET/MRI (21.5) was closer to surgical PCI (24.5) (p = 0.6), than DW-MRI (median PCI 20.0, p = 0.007). However, both methods were highly correlated with the surgical PCI (PET/MRI: β = 0.94 p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1470-7330 |
| Relation: |
https://doaj.org/toc/1470-7330 |
| DOI: |
10.1186/s40644-021-00399-2 |
| Access URL: |
https://doaj.org/article/5d524079961e423b85fbed9fd71a63bb |
| Accession Number: |
edsdoj.5d524079961e423b85fbed9fd71a63bb |
| Database: |
Directory of Open Access Journals |
