Molecular epidemiology of influenza A/H3N2 viruses circulating in Mexico from 2003 to 2012.
| Title: | Molecular epidemiology of influenza A/H3N2 viruses circulating in Mexico from 2003 to 2012. |
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| Authors: | Marina Escalera-Zamudio, Martha I Nelson, Ana Georgina Cobián Güemes, Irma López-Martínez, Natividad Cruz-Ortiz, Miguel Iguala-Vidales, Elvia Rodríguez García, Gisela Barrera-Badillo, Jose Alberto Díaz-Quiñonez, Susana López, Carlos F Arias, Pavel Isa, Members of Colegio de Pediatría del Estado de Veracruz |
| Source: | PLoS ONE, Vol 9, Iss 7, p e102453 (2014) |
| Publisher Information: | Public Library of Science (PLoS), 2014. |
| Publication Year: | 2014 |
| Collection: | LCC:Medicine LCC:Science |
| Subject Terms: | Medicine, Science |
| More Details: | In this work, nineteen influenza A/H3N2 viruses isolated in Mexico between 2003 and 2012 were studied. Our findings show that different human A/H3N2 viral lineages co-circulate within a same season and can also persist locally in between different influenza seasons, increasing the chance for genetic reassortment events. A novel minor cluster was also identified, named here as Korea, that circulated worldwide during 2003. Frequently, phylogenetic characterization did not correlate with the determined antigenic identity, supporting the need for the use of molecular evolutionary tools additionally to antigenic data for the surveillance and characterization of viral diversity during each flu season. This work represents the first long-term molecular epidemiology study of influenza A/H3N2 viruses in Mexico based on the complete genomic sequences and contributes to the monitoring of evolutionary trends of A/H3N2 influenza viruses within North and Central America. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1932-6203 40142159 |
| Relation: | http://europepmc.org/articles/PMC4116128?pdf=render; https://doaj.org/toc/1932-6203 |
| DOI: | 10.1371/journal.pone.0102453 |
| Access URL: | https://doaj.org/article/5d3aa976f40142159dc0e80dad167a05 |
| Accession Number: | edsdoj.5d3aa976f40142159dc0e80dad167a05 |
| Database: | Directory of Open Access Journals |
| ISSN: | 19326203 40142159 |
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| DOI: | 10.1371/journal.pone.0102453 |
| Published in: | PLoS ONE |
| Language: | English |