| Title: |
Endothelial pannexin-1 channels modulate macrophage and smooth muscle cell activation in abdominal aortic aneurysm formation |
| Authors: |
Amanda C. Filiberto, Michael D. Spinosa, Craig T. Elder, Gang Su, Victoria Leroy, Zachary Ladd, Guanyi Lu, J. Hunter Mehaffey, Morgan D. Salmon, Robert B. Hawkins, Kodi S. Ravichandran, Brant E. Isakson, Gilbert R. Upchurch, Ashish K. Sharma |
| Source: |
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022) |
| Publisher Information: |
Nature Portfolio, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
Pannexin-1 ion channels on endothelial cells regulate vascular inflammation and remodeling to mediate aortic aneurysm formation. Pharmacological blockade of Pannexin-1 channels may offer translational therapeutic mitigation of aneurysmal pathology. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-022-29233-4 |
| Access URL: |
https://doaj.org/article/5d2bdb9d8cc044ab83c636b0eec19b6c |
| Accession Number: |
edsdoj.5d2bdb9d8cc044ab83c636b0eec19b6c |
| Database: |
Directory of Open Access Journals |
