Chemical analysis and concentrations of cannabidiol substances used for refractory epilepsy in Chilean patients. An underestimated worldwide risk

Bibliographic Details
Title: Chemical analysis and concentrations of cannabidiol substances used for refractory epilepsy in Chilean patients. An underestimated worldwide risk
Authors: Loreto Ríos‐Pohl, Macarena Franco, Daniel Navea, Viviana Venegas, Tomás Cerda
Source: Epilepsia Open, Vol 9, Iss 6, Pp 2546-2552 (2024)
Publisher Information: Wiley, 2024.
Publication Year: 2024
Collection: LCC:Neurology. Diseases of the nervous system
Subject Terms: cannabidiol, cannabidiol and epilepsy, CBD, homemade CBD, Neurology. Diseases of the nervous system, RC346-429
More Details: Abstract Objective The purpose of this study is to analyze composition of HMS (homemade CBD), NLS (non‐licensed commercial products), and bioequivalent CBD (BES) collected from Chilean patients that voluntary accepted to analyze the “CBD‐substance.” Methods Samples were collected through an open invitation for different patients to anonymously and free of charge participate in the analysis of CBD oil. The analysis of the active principle was performed using High‐Resolution Liquid Chromatography (HPLC). Results A total of 35 samples were collected between March 2020 and September 2021, including two BES, six NLS, and 27 HMS products. The BES had an average CBD concentration of 89.15 mg/mL and an average THC concentration of 0.015 mg/mL, which complied with the maximum THC levels required by regulatory authorities (
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2470-9239
Relation: https://doaj.org/toc/2470-9239
DOI: 10.1002/epi4.13081
Access URL: https://doaj.org/article/5c755aabb64e4851aae3adc1d110f68c
Accession Number: edsdoj.5c755aabb64e4851aae3adc1d110f68c
Database: Directory of Open Access Journals
More Details
ISSN:24709239
DOI:10.1002/epi4.13081
Published in:Epilepsia Open
Language:English