Bibliographic Details
Title: |
Chemical analysis and concentrations of cannabidiol substances used for refractory epilepsy in Chilean patients. An underestimated worldwide risk |
Authors: |
Loreto Ríos‐Pohl, Macarena Franco, Daniel Navea, Viviana Venegas, Tomás Cerda |
Source: |
Epilepsia Open, Vol 9, Iss 6, Pp 2546-2552 (2024) |
Publisher Information: |
Wiley, 2024. |
Publication Year: |
2024 |
Collection: |
LCC:Neurology. Diseases of the nervous system |
Subject Terms: |
cannabidiol, cannabidiol and epilepsy, CBD, homemade CBD, Neurology. Diseases of the nervous system, RC346-429 |
More Details: |
Abstract Objective The purpose of this study is to analyze composition of HMS (homemade CBD), NLS (non‐licensed commercial products), and bioequivalent CBD (BES) collected from Chilean patients that voluntary accepted to analyze the “CBD‐substance.” Methods Samples were collected through an open invitation for different patients to anonymously and free of charge participate in the analysis of CBD oil. The analysis of the active principle was performed using High‐Resolution Liquid Chromatography (HPLC). Results A total of 35 samples were collected between March 2020 and September 2021, including two BES, six NLS, and 27 HMS products. The BES had an average CBD concentration of 89.15 mg/mL and an average THC concentration of 0.015 mg/mL, which complied with the maximum THC levels required by regulatory authorities ( |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2470-9239 |
Relation: |
https://doaj.org/toc/2470-9239 |
DOI: |
10.1002/epi4.13081 |
Access URL: |
https://doaj.org/article/5c755aabb64e4851aae3adc1d110f68c |
Accession Number: |
edsdoj.5c755aabb64e4851aae3adc1d110f68c |
Database: |
Directory of Open Access Journals |