Academic Journal
Noninvasive evaluation of the hemodynamic status in patients after heart transplantation or left ventricular assist device implantation
| Title: | Noninvasive evaluation of the hemodynamic status in patients after heart transplantation or left ventricular assist device implantation |
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| Authors: | Sebastian Roth, Henrik Fox, René M’Pembele, Michiel Morshuis, Giovanna Lurati Buse, Markus W. Hollmann, Ragnar Huhn, Thomas Bitter |
| Source: | PLoS ONE, Vol 17, Iss 10 (2022) |
| Publisher Information: | Public Library of Science (PLoS), 2022. |
| Publication Year: | 2022 |
| Collection: | LCC:Medicine LCC:Science |
| Subject Terms: | Medicine, Science |
| More Details: | Introduction Hemodynamic assessment is crucial after heart transplantation (HTX) or left ventricular assist device (LVAD) implantation. Gold-standard is invasive assessment via thermodilution (TD). Noninvasive pulse contour analysis (NPCA) is a new technology that is supposed to determine hemodynamics completely noninvasive. We aimed to validate this technology in HTX and LVAD patients and conducted a prospective single-center cohort study. Methods Patients after HTX or LVAD implantation underwent right heart catheterization including TD. NPCA using the CNAP Monitor (V.5.2.14; CNSystems Medizintechnik AG, Graz, Austria) was performed simultaneously. Three TD measurements were compared with simultaneous NPCA measurements for hemodynamic assessment. To describe the agreement between TD and NPCA, Bland–Altman analysis was done. Results In total, 28 patients were prospectively enrolled (HTX: n = 10, LVAD: n = 18). Bland-Altman analysis revealed a mean bias of +1.05 l/min (limits of agreement ± 4.09 l/min, percentage error 62.1%) for cardiac output (CO). In LVAD patients, no adequate NPCA signal could be obtained. In 5 patients (27.8%), any NPCA signal could be detected, but was considered as low signal quality. Conclusion In conclusion, according to our limited data in a small cohort of HTX and LVAD patients, NPCA using the CNAP Monitor seems not to be suitable for noninvasive evaluation of the hemodynamic status. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1932-6203 |
| Relation: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9565384/?tool=EBI; https://doaj.org/toc/1932-6203 |
| Access URL: | https://doaj.org/article/5bf778399ff34a4fb846eb6408965b85 |
| Accession Number: | edsdoj.5bf778399ff34a4fb846eb6408965b85 |
| Database: | Directory of Open Access Journals |
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| ISSN: | 19326203 |
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| Published in: | PLoS ONE |
| Language: | English |