Large T‐cell extradural lymphoma with concurrent marked cerebrospinal fluid eosinophilia in a dog
| Title: | Large T‐cell extradural lymphoma with concurrent marked cerebrospinal fluid eosinophilia in a dog |
|---|---|
| Authors: | Anna M. Massie, Katherine Skorupski, William Vernau, Ehren McLarty, Rachel V. Brady, Karen M. Vernau |
| Source: | Journal of Veterinary Internal Medicine, Vol 37, Iss 6, Pp 2492-2497 (2023) |
| Publisher Information: | Wiley, 2023. |
| Publication Year: | 2023 |
| Collection: | LCC:Veterinary medicine |
| Subject Terms: | ataxia, CHOP, decompression, neoplasia, Veterinary medicine, SF600-1100 |
| More Details: | Abstract A 3‐year‐old male pit bull terrier was presented for a 4‐day history of progressive tetraparesis and cervical pain. Magnetic resonance imaging confirmed an extradural mass within the left lateral vertebral canal extending from caudal C5 to mid‐T2. Lumbar cerebrospinal fluid (CSF) demonstrated marked (90%) eosinophilic inflammation. A C6‐7 dorsal laminectomy and C7‐T2 left hemilaminectomy were done, with gross disease remaining. Histopathology revealed a large T cell lymphoma with marked eosinophilic infiltration. The dog underwent CHOP‐based chemotherapy with resolution of clinical signs, with a similar course of therapy performed at recurrence 37 months after initial presentation. The dog was euthanized 39 months after presentation for multiorgan failure secondary to neutropenic sepsis and aspiration pneumonia. This represents a positive long‐term response to multimodal treatment of extradural T‐cell lymphoma within the vertebral canal associated with a marked CSF eosinophilia. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1939-1676 0891-6640 |
| Relation: | https://doaj.org/toc/0891-6640; https://doaj.org/toc/1939-1676 |
| DOI: | 10.1111/jvim.16854 |
| Access URL: | https://doaj.org/article/5b567bb5c6594bb28ccae55eb2550cf6 |
| Accession Number: | edsdoj.5b567bb5c6594bb28ccae55eb2550cf6 |
| Database: | Directory of Open Access Journals |
| ISSN: | 19391676 08916640 |
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| DOI: | 10.1111/jvim.16854 |
| Published in: | Journal of Veterinary Internal Medicine |
| Language: | English |