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Cancer Clinical Trials in Africa—An Untapped Opportunity: Recommendations From AORTIC 2019 Conference Special Interest Group in Clinical Trials

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Title: Cancer Clinical Trials in Africa—An Untapped Opportunity: Recommendations From AORTIC 2019 Conference Special Interest Group in Clinical Trials
Authors: Abiola Ibraheem, Colin Pillai, Ifeoma Okoye, J. Joshua Smith, Diane Reidy-Lagunes, Grace Macaulay, Olusegun Alatise
Source: JCO Global Oncology, Vol , Iss 7, Pp 1358-1363 (2021)
Publisher Information: American Society of Clinical Oncology, 2021.
Publication Year: 2021
Collection: LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
More Details: Cancer is now a formidable health care burden in sub-Saharan Africa (SSA) due to lifestyle westernization and longer life expectancy. The exponential increase in cancer incidence coupled with high mortality rate is not comparable with that seen in westernized countries. To address global cancer disparity, globalization of cancer clinical trials to involve sub-Saharan Africa can serve as a platform where innovative targeted therapies can be made available to patients in the environ. In the 2019 African Organization for Research and Training in Cancer (AORTIC) conference held at Maputo, Mozambique, a group of clinical trialists spanning across multiple continents highlighted the opportunities in Africa for the conduct of cancer clinical trials. The secondary purpose of the meeting was to address the belief that Africa was incapable of conducting interventional cancer trials but showed the in-continent strengths, such as available capacities, trained local clinical trialists with clinical trial experiences, clinical trial consortia, local capabilities, mapping out logistics, ethical consideration, political will, real-time benefits of clinical trials to clinical practice, and future directions for trials.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2687-8941
Relation: https://doaj.org/toc/2687-8941
DOI: 10.1200/GO.21.00096
Access URL: https://doaj.org/article/5b0f95750cc344848f9b5b7a75b76187
Accession Number: edsdoj.5b0f95750cc344848f9b5b7a75b76187
Database: Directory of Open Access Journals
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  Data: Cancer Clinical Trials in Africa—An Untapped Opportunity: Recommendations From AORTIC 2019 Conference Special Interest Group in Clinical Trials
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  Data: <searchLink fieldCode="AR" term="%22Abiola+Ibraheem%22">Abiola Ibraheem</searchLink><br /><searchLink fieldCode="AR" term="%22Colin+Pillai%22">Colin Pillai</searchLink><br /><searchLink fieldCode="AR" term="%22Ifeoma+Okoye%22">Ifeoma Okoye</searchLink><br /><searchLink fieldCode="AR" term="%22J%2E+Joshua+Smith%22">J. Joshua Smith</searchLink><br /><searchLink fieldCode="AR" term="%22Diane+Reidy-Lagunes%22">Diane Reidy-Lagunes</searchLink><br /><searchLink fieldCode="AR" term="%22Grace+Macaulay%22">Grace Macaulay</searchLink><br /><searchLink fieldCode="AR" term="%22Olusegun+Alatise%22">Olusegun Alatise</searchLink>
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  Data: JCO Global Oncology, Vol , Iss 7, Pp 1358-1363 (2021)
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  Data: LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
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  Data: Cancer is now a formidable health care burden in sub-Saharan Africa (SSA) due to lifestyle westernization and longer life expectancy. The exponential increase in cancer incidence coupled with high mortality rate is not comparable with that seen in westernized countries. To address global cancer disparity, globalization of cancer clinical trials to involve sub-Saharan Africa can serve as a platform where innovative targeted therapies can be made available to patients in the environ. In the 2019 African Organization for Research and Training in Cancer (AORTIC) conference held at Maputo, Mozambique, a group of clinical trialists spanning across multiple continents highlighted the opportunities in Africa for the conduct of cancer clinical trials. The secondary purpose of the meeting was to address the belief that Africa was incapable of conducting interventional cancer trials but showed the in-continent strengths, such as available capacities, trained local clinical trialists with clinical trial experiences, clinical trial consortia, local capabilities, mapping out logistics, ethical consideration, political will, real-time benefits of clinical trials to clinical practice, and future directions for trials.
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