Association of remnant cholesterol with sarcopenia in Korean adults: a nationwide population-based study using data from the KNHANES

Bibliographic Details
Title: Association of remnant cholesterol with sarcopenia in Korean adults: a nationwide population-based study using data from the KNHANES
Authors: Soo Yeon Jang, Soon-Young Hwang, Ahreum Jang, Kyeong Jin Kim, Ji Hee Yu, Nam Hoon Kim, Hye Jin Yoo, Nan Hee Kim, Sei Hyun Baik, Kyung Mook Choi
Source: Frontiers in Endocrinology, Vol 15 (2024)
Publisher Information: Frontiers Media S.A., 2024.
Publication Year: 2024
Collection: LCC:Diseases of the endocrine glands. Clinical endocrinology
Subject Terms: remnant cholesterol, dyslipidemia, sarcopenia, muscle mass, triglyceride-rich lipoproteins, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
More Details: BackgroundMounting evidence indicates the importance of the interplay between skeletal muscles and lipid metabolism. Remnant cholesterol (remnant-C) is considered one of the principal residual risk factors for cardiovascular disease and metabolic disorders; however, there are limited studies on the impact of remnant-C on sarcopenia.MethodsData from the Korea National Health and Nutrition Examination Surveys (KNHANES) between 2008 and 2011 were used in this nationwide population-based study. In total, 17,408 participants were enrolled in this study. The subjects were categorized into four groups according to the quartile of remnant-C values. We conducted multivariable logistic regression analysis to evaluate the association between remnant-C and muscle mass measured using dual-energy X-ray absorptiometry.ResultsA total of 1,791 participants (10.3%) presented low muscle mass, and there was a sequential increase in the percentage of low muscle mass across remnant-C quartiles (Q1, 5.2%; Q2, 8.7%; Q3, 11.5%; Q4, 15.7%). In the full adjusted model, those in the highest remnant-C quartile group showed significantly increased odds ratio (OR) for low muscle mass compared with those in the lowest remnant-C group after adjusting for various confounding factors (OR = 1.33, 95% confidence interval (CI) = 1.06–1.68, P
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1664-2392
Relation: https://www.frontiersin.org/articles/10.3389/fendo.2024.1391733/full; https://doaj.org/toc/1664-2392
DOI: 10.3389/fendo.2024.1391733
Access URL: https://doaj.org/article/ae5af8bbdfac4b2690391b73984d20cd
Accession Number: edsdoj.5af8bbdfac4b2690391b73984d20cd
Database: Directory of Open Access Journals
More Details
ISSN:16642392
DOI:10.3389/fendo.2024.1391733
Published in:Frontiers in Endocrinology
Language:English