Academic Journal
Prevalence of elevated liver enzymes and its relationship with type 2 diabetes mellitus in North Indian adults
| Title: | Prevalence of elevated liver enzymes and its relationship with type 2 diabetes mellitus in North Indian adults |
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| Authors: | Sana Alam, Alok Raghav, Alisha Reyaz, Akif Ahsan, Ashok Kumar Ahirwar, Vineet Jain, Saurabh Agarwal, Prashant Tripathi |
| Source: | Metabolism Open, Vol 12, Iss , Pp 100130- (2021) |
| Publisher Information: | Elsevier, 2021. |
| Publication Year: | 2021 |
| Collection: | LCC:Physiology LCC:Biochemistry |
| Subject Terms: | Diabetes mellitus type 2, Liver function tests, Liver, Hepatic pathology, Physiology, QP1-981, Biochemistry, QD415-436 |
| More Details: | Background: Non-alcoholic fatty liver disease (NAFLD) also referred as metabolic as metabolic (dysfunction) associated fatty liver disease. Type 2 diabetes mellitus (T2DM) is a major cause in progression of NAFLD and non-alcoholic steatohepatitis (NASH). The aim of the present study is to assess the activity of liver enzymes in T2DM in North Indian population. Method: This was a cross-sectional descriptive study clinic-based study in patients with T2DM. A total of 612 participants (226 healthy controls and 386 T2DM) were recruited. Body mass index (BMI), activity of liver enzymes including alanine and aspartate aminotransferase (ALT, AST) along with alkaline phosphatase (ALP) was measured. Fasting blood glucose (FBG) and glycosylated hemoglobin (HbA1c) along with total protein (TP) and albumin were also measured. Quantitative variables were expressed as mean ± SD, while qualitative variables as frequencies (%). Pearson/Spearman correlation test, unpaired t-test, Chi-squared test was used to assess the correlation, association and significant differences between study groups respectively. A P-value of |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 2589-9368 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2589936821000542; https://doaj.org/toc/2589-9368 |
| DOI: | 10.1016/j.metop.2021.100130 |
| Access URL: | https://doaj.org/article/5a8dec94f6e94c8ba01cee2b916b8c61 |
| Accession Number: | edsdoj.5a8dec94f6e94c8ba01cee2b916b8c61 |
| Database: | Directory of Open Access Journals |
| ISSN: | 25899368 |
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| DOI: | 10.1016/j.metop.2021.100130 |
| Published in: | Metabolism Open |
| Language: | English |