Bibliographic Details
| Title: |
Generation of two human induced pluripotent stem cell lines with BAX and BAK1 double knock-out using CRISPR/Cas9 |
| Authors: |
Katarzyna Anna Ludwik, Lina Hellwig, Tanja Fisch, Jörg Contzen, Claudia Schaar, Philipp Mergenthaler, Harald Stachelscheid |
| Source: |
Stem Cell Research, Vol 76, Iss , Pp 103377- (2024) |
| Publisher Information: |
Elsevier, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Biology (General) |
| Subject Terms: |
Biology (General), QH301-705.5 |
| More Details: |
Bcl-2-associated X protein (BAX) and Blc-2 homologous antagonist killer 1 (BAK) are two pro-apoptotic members of BCL2 family. Here, two BAX/BAK double knock-out human induced pluripotent stem cell lines (iPSC) we generated using CRISPR-Cas9 to generate apoptosis incompetent cell lines. The resulting cell lines were karyotypically normal, had typical morphology and expressed typical markers for the undifferentiated state. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1873-5061 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S1873506124000758; https://doaj.org/toc/1873-5061 |
| DOI: |
10.1016/j.scr.2024.103377 |
| Access URL: |
https://doaj.org/article/dd5a739942364f8e8de24e811ee7c18a |
| Accession Number: |
edsdoj.5a739942364f8e8de24e811ee7c18a |
| Database: |
Directory of Open Access Journals |
