Impact of surface topography and coating on osteogenesis and bacterial attachment on titanium implants

Bibliographic Details
Title: Impact of surface topography and coating on osteogenesis and bacterial attachment on titanium implants
Authors: Laila Damiati, Marcus G Eales, Angela H Nobbs, Bo Su, Penelope M Tsimbouri, Manuel Salmeron-Sanchez, Matthew J Dalby
Source: Journal of Tissue Engineering, Vol 9 (2018)
Publisher Information: SAGE Publishing, 2018.
Publication Year: 2018
Collection: LCC:Biochemistry
Subject Terms: Biochemistry, QD415-436
More Details: Titanium (Ti) plays a predominant role as the material of choice in orthopaedic and dental implants. Despite the majority of Ti implants having long-term success, premature failure due to unsuccessful osseointegration leading to aseptic loosening is still too common. Recently, surface topography modification and biological/non-biological coatings have been integrated into orthopaedic/dental implants in order to mimic the surrounding biological environment as well as reduce the inflammation/infection that may occur. In this review, we summarize the impact of various Ti coatings on cell behaviour both in vivo and in vitro. First, we focus on the Ti surface properties and their effects on osteogenesis and then on bacterial adhesion and viability. We conclude from the current literature that surface modification of Ti implants can be generated that offer both osteoinductive and antimicrobial properties.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2041-7314
20417314
Relation: https://doaj.org/toc/2041-7314
DOI: 10.1177/2041731418790694
Access URL: https://doaj.org/article/a5a64507a5ce4787a78e11a928dbf4cb
Accession Number: edsdoj.5a64507a5ce4787a78e11a928dbf4cb
Database: Directory of Open Access Journals
More Details
ISSN:20417314
DOI:10.1177/2041731418790694
Published in:Journal of Tissue Engineering
Language:English