Bibliographic Details
| Title: |
A comparison of the real world effectiveness of catheter ablation and drug therapy in atrial fibrillation patients in a Chinese setting |
| Authors: |
Xin Du, Lizhu Guo, Xiaonan He, Yu Jia, Jiahui Wu, Deyong Long, Ronghui Yu, Caihua Sang, Xiaohui Liu, Hongjun Yin, Jianwei Xuan, Jianzeng Dong, Changsheng Ma |
| Source: |
BMC Cardiovascular Disorders, Vol 17, Iss 1, Pp 1-9 (2017) |
| Publisher Information: |
BMC, 2017. |
| Publication Year: |
2017 |
| Collection: |
LCC:Diseases of the circulatory (Cardiovascular) system |
| Subject Terms: |
Catheter ablation, Atrial fibrillation, Anti-arrhythmic drugs, Quality of life, Chinese, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| More Details: |
Abstract Background Studies have demonstrated that catheter ablation of atrial fibrillation is associated with better rhythm control than drug therapy. The present study aimed to assess the clinical outcomes and health-related quality of life of ablation therapy in a real world setting. Methods A prospective, non-randomized, single center study in a real-world clinical setting in China was conducted. Patients were followed up at 3, 6, and 9 months after baseline encounter. Propensity score matched patients receiving ablation or anti-arrhythmic drug therapy were compared. Incidence rate of atrial fibrillation recurrence and quality of life outcomes were measured and analyzed using log-rank test, multivariate logistic regression and mixed-effects linear regression respectively. Results In this study, 151 atrial fibrillation patients treated by ablation therapy and 318 patients treated by anti-arrhythmic drugs were enrolled. During follow up, 82.0% in the ablation arm and 22.4% in the drug arm had no documented atrial fibrillation recurrence [HR for atrial fibrillation recurrence 0.07 (95%CI: 0.02–0.21, p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1471-2261 |
| Relation: |
http://link.springer.com/article/10.1186/s12872-017-0634-y; https://doaj.org/toc/1471-2261 |
| DOI: |
10.1186/s12872-017-0634-y |
| Access URL: |
https://doaj.org/article/59ea99c21d1c41deb2d7f66f36a99ad7 |
| Accession Number: |
edsdoj.59ea99c21d1c41deb2d7f66f36a99ad7 |
| Database: |
Directory of Open Access Journals |
