End-to-end design of multicolor scintillators for enhanced energy resolution in X-ray imaging

Bibliographic Details
Title: End-to-end design of multicolor scintillators for enhanced energy resolution in X-ray imaging
Authors: Seokhwan Min, Seou Choi, Simo Pajovic, Sachin Vaidya, Nicholas Rivera, Shanhui Fan, Marin Soljačić, Charles Roques-Carmes
Source: Light: Science & Applications, Vol 14, Iss 1, Pp 1-12 (2025)
Publisher Information: Nature Publishing Group, 2025.
Publication Year: 2025
Collection: LCC:Applied optics. Photonics
LCC:Optics. Light
Subject Terms: Applied optics. Photonics, TA1501-1820, Optics. Light, QC350-467
More Details: Abstract Scintillators have been widely used in X-ray imaging due to their ability to convert high-energy radiation into visible light, making them essential for applications such as medical imaging and high-energy physics. Recent advances in the artificial structuring of scintillators offer new opportunities for improving the energy resolution of scintillator-based X-ray detectors. Here, we present a three-bin energy-resolved X-ray imaging framework based on a three-layer multicolor scintillator used in conjunction with a physics-aware image postprocessing algorithm. The multicolor scintillator is able to preserve X-ray energy information through the combination of emission wavelength multiplexing and energy-dependent isolation of X-ray absorption in specific layers. The dominant emission color and the radius of the spot measured by the detector are used to infer the incident X-ray energy based on prior knowledge of the energy-dependent absorption profiles of the scintillator stack. Through ab initio Monte Carlo simulations, we show that our approach can achieve an energy reconstruction accuracy of 49.7%, which is only 2% below the maximum accuracy achievable with realistic scintillators. We apply our framework to medical phantom imaging simulations where we demonstrate that it can effectively differentiate iodine and gadolinium-based contrast agents from bone, muscle, and soft tissue.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2047-7538
Relation: https://doaj.org/toc/2047-7538
DOI: 10.1038/s41377-025-01836-8
Access URL: https://doaj.org/article/582f1f5b9a154535afda7af70e2bfc17
Accession Number: edsdoj.582f1f5b9a154535afda7af70e2bfc17
Database: Directory of Open Access Journals
More Details
ISSN:20477538
DOI:10.1038/s41377-025-01836-8
Published in:Light: Science & Applications
Language:English