Bibliographic Details
| Title: |
Chemical composition and biological activity of Baccharis erioclada DC. essential oil |
| Authors: |
Vanessa Barbosa Bobek, Luiza Stolz Cruz, Camila Freitas de Oliveira, Fernando Cesar Martins Betim, Juliane Nadal Dias Swiech, Daniela Gaspardo Folquitto, Carmen Antonia Sanches Ito, Jane Manfron Budel, Sandra Maria Warumby Zanin, Josiane de Fátima Padilha de Paula, Obdúlio Gomes Miguel |
| Source: |
Brazilian Journal of Pharmaceutical Sciences, Vol 58 (2022) |
| Publisher Information: |
Universidade de São Paulo, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Pharmacy and materia medica |
| Subject Terms: |
Volatile oil, Asteraceae, Vassoura-lageana, Pharmacy and materia medica, RS1-441 |
| More Details: |
Abstract The chemically complex essential oils of Baccharis species are associated with several biological activities, such as antimicrobial and antiulcerous properties. However, few studies have investigated Baccharis erioclada DC. Therefore, in this study, we aimed to characterize the essential oil of B. erioclada and evaluate its antioxidant, antimicrobial, and hemolytic potential. The essential oil was extracted by hydrodistillation using a Clevenger apparatus and analyzed via gas chromatography-mass spectrometry (GC-MS). Phosphomolybdenum complex formation, reducing antioxidant power, and thiobarbituric acid reactive substances (TBARS) methods were used to determine antioxidant potential. To evaluate the essential oil’s antimicrobial activity, minimum inhibitory concentrations (MIC) in Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Candida albicans were calculated. Hemolytic activity was determined in sheep red blood cells. Thirty-one compounds were identified via GC-MS analysis, representing 81.60% of the total essential oil. These compounds included: turmerone (27.97%), fokienol (13.47%), ledol (9.78%), and santalol (5.35%). The class of compounds identified was the oxygenated sesquiterpenes (62.52%). Antioxidant activity was confirmed via phosphomolybdenum complex formation and TBARS methods. Moderate antimicrobial activity and low hemolysis rates were displayed at concentrations of 250 and 500 μg/mL. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2175-9790 |
| Relation: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100571&lng=en&tlng=en; http://www.scielo.br/pdf/bjps/v58/2175-9790-bjps-58-e19118.pdf; https://doaj.org/toc/2175-9790 |
| DOI: |
10.1590/s2175-97902022e19118 |
| Access URL: |
https://doaj.org/article/ea57658f3051425ca6cc691ab2f53e42 |
| Accession Number: |
edsdoj.57658f3051425ca6cc691ab2f53e42 |
| Database: |
Directory of Open Access Journals |
