Bibliographic Details
| Title: |
TNF is a potential therapeutic target to suppress prostatic inflammation and hyperplasia in autoimmune disease |
| Authors: |
Renee E. Vickman, LaTayia Aaron-Brooks, Renyuan Zhang, Nadia A. Lanman, Brittany Lapin, Victoria Gil, Max Greenberg, Takeshi Sasaki, Gregory M. Cresswell, Meaghan M. Broman, J. Sebastian Paez, Jacqueline Petkewicz, Pooja Talaty, Brian T. Helfand, Alexander P. Glaser, Chi-Hsiung Wang, Omar E. Franco, Timothy L. Ratliff, Kent L. Nastiuk, Susan E. Crawford, Simon W. Hayward |
| Source: |
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022) |
| Publisher Information: |
Nature Portfolio, 2022. |
| Publication Year: |
2022 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
Reduction of systemic autoimmunity using TNF blockers may also reduce inflammatory diseases in other organs. Here, the authors use a patient database and scRNA-seq to link autoimmune diseases to benign prostatic hyperplasia (BPH), and demonstrate that prostatic hyperplasia is reduced by TNF blockers in humans and mice. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-022-29719-1 |
| Access URL: |
https://doaj.org/article/572e6df1a2f4471bb53b3a820ff54a37 |
| Accession Number: |
edsdoj.572e6df1a2f4471bb53b3a820ff54a37 |
| Database: |
Directory of Open Access Journals |
