Deoxynivalenol Determination Using Innovative Lateral Flow Device Technology

Bibliographic Details
Title: Deoxynivalenol Determination Using Innovative Lateral Flow Device Technology
Authors: Halberstadt Delphine, Giorni Paola, Barato Erica, Bertuzzi Terenzio
Source: Toxins, Vol 17, Iss 3, p 123 (2025)
Publisher Information: MDPI AG, 2025.
Publication Year: 2025
Collection: LCC:Medicine
Subject Terms: deoxynivalenol, lateral flow device technology, LC-MS/MS analysis, Medicine
More Details: Deoxynivalenol (DON), generally the most widespread mycotoxin in wheat, is regulated by the EU regulation in cereals and cereal-derived products. Its presence can be detected by chromatographic or rapid methods; the latter technique is generally used in control analysis, fulfilling the needs of the stakeholders of the wheat grain chain. Lateral flow strips are often used for the rapid detection of different mycotoxins in several agricultural products; regarding DON determination, different lateral flow immunochromatography strips are currently available, also providing quantitative results. The purpose of this work was to evaluate the accuracy of an innovative lateral flow device coupled to a bench top device, following a digital approach. The proposed method was compared to an LC-MS/MS method, analyzing 50 naturally contaminated wheat samples. The results obtained using the two methods were very similar and, applying a paired t-test, the mean difference between measurements resulted not significantly different (α = 0.003). The correlation between the results showed a slope of the line close to 1 (m = 0.9904) and a regression coefficient (r) of 0.9968.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2072-6651
Relation: https://www.mdpi.com/2072-6651/17/3/123; https://doaj.org/toc/2072-6651
DOI: 10.3390/toxins17030123
Access URL: https://doaj.org/article/5650741ed24840a28adeeb380c5a46a7
Accession Number: edsdoj.5650741ed24840a28adeeb380c5a46a7
Database: Directory of Open Access Journals
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More Details
ISSN:20726651
DOI:10.3390/toxins17030123
Published in:Toxins
Language:English